Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a highly prevalent breathing
disorder in sleep that is an independent risk factor for cardiovascular morbidity and mortality …

Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are
conditions with high mortality and serious long-term physical and cognitive disabilities. They …

Inflammation is an underlying feature of a variety of human diseases. An important
manifestation of this pathophysiological response is microvascular dysfunction, which …

Leukocytes are recruited into the cerebral microcirculation following an ischemic insult. The
leukocyte–endothelial cell adhesion manifested within a few hours after ischemia (followed …

Salidroside (Sal) is a bioactive extract principally from traditional herbal medicine such as
Rhodiola rosea L., which has been commonly used for hundreds of years in Asia countries …

The microcirculation is highly responsive to, and a vital participant in, the inflammatory
response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit …

Obstructive sleep apnea (OSA), a highly prevalent breathing disorder in sleep, characterized
by intermittent and recurrent pauses in respiration, has emerged as an independent risk …

Twenty-four percent of sickle cell disease (SCD) patients have a stroke by the age of 45
years. Blood transfusions decrease stroke risk in patients deemed high risk by transcranial …

Objectives: During critical illness, impaired endothelial vascular reactivity predicts prolonged
acute brain dysfunction, but relationships between endothelial activation, blood-brain …

Objective: Brief systemic hypoxia protects the rodent brain from subsequent ischemic injury,
although the protection wanes within days. We hypothesized that the duration of ischemic …