Nanodelivery of nucleic acids
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
Alzheimer's disease: pathogenesis, diagnostics, and therapeutics
Currently, 47 million people live with dementia globally, and it is estimated to increase more
than threefold (~ 131 million) by 2050. Alzheimer's disease (AD) is one of the major …
than threefold (~ 131 million) by 2050. Alzheimer's disease (AD) is one of the major …
Multifunctional gold nanoparticles for improved diagnostic and therapeutic applications: a review
The medical properties of metals have been explored for centuries in traditional medicine for
the treatment of infections and diseases and still practiced to date. Platinum-based drugs are …
the treatment of infections and diseases and still practiced to date. Platinum-based drugs are …
The amyloid-β oligomer hypothesis: beginning of the third decade
The amyloid-β oligomer (AβO) hypothesis was introduced in 1998. It proposed that the brain
damage leading to Alzheimer's disease (AD) was instigated by soluble, ligand-like AβOs …
damage leading to Alzheimer's disease (AD) was instigated by soluble, ligand-like AβOs …
The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles
A Abdal Dayem, MK Hossain, SB Lee, K Kim… - International journal of …, 2017 - mdpi.com
Nanoparticles (NPs) possess unique physical and chemical properties that make them
appropriate for various applications. The structural alteration of metallic NPs leads to …
appropriate for various applications. The structural alteration of metallic NPs leads to …
Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …
nanomaterials in biological environments is essential for safe and effective biomedical …
Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention
YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …
insidious age-related neurodegenerative disease and is presently considered a global …
[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal
R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …
Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …
disease in incidence. Despite significant worldwide investment in research, cancer remains …
Alzheimer disease pathogenesis: insights from molecular and cellular biology studies of oligomeric Aβ and tau species
XQ Chen, WC Mobley - Frontiers in Neuroscience, 2019 - frontiersin.org
Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary human and financial burdens. Studies of …
treatment promises to exact extraordinary human and financial burdens. Studies of …