Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

Nephrotoxicity (NT) is a renal-specific situation caused by different toxins and drugs like non-
steroidal anti-inflammatory drugs (NSAIDs). NSAIDs like diclofenac (DCF) lead to glomerular …

Doxorubicin (DOX) is an anthracycline drug used for cancer treatment. However, its
treatment is contiguous with toxic effects. We examined the nephroprotective potential of A …

Doxorubicin (DXR) is one of the most important chemotherapeutic agent. However,
nephrotoxicity reduces its clinical utility in humans. The aim of the study was to investigate …

Background This study aimed to evaluate the protective effects of alamandine, a new
member of the angiotensin family, against doxorubicin (DOX)-induced nephrotoxicity in rats …

Objective: Doxorubicin (DXR) is an anticancer drug used in the treatment of many human
malignancies. However, its clinical use is limited because of several side effects like …

Aims Doxorubicin is a prominent anticancer agent. However, its organotoxic potential has
restricted its clinical use. The current study was performed to investigate the protective effect …

The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …