Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

Environmental pH modulation by pathogenic fungi as a strategy to conquer the host

S Vylkova - PLoS pathogens, 2017 - journals.plos.org
The ability of microorganisms to sense and adapt to changes in the environment is essential
to their survival. This is particularly important for species with an intimate association with …

Enterococcus faecalis bacteriocin EntV inhibits hyphal morphogenesis, biofilm formation, and virulence of Candida albicans

CE Graham, MR Cruz, DA Garsin… - Proceedings of the …, 2017 - National Acad Sciences
Enterococcus faecalis, a Gram-positive bacterium, and Candida albicans, a fungus, occupy
overlapping niches as ubiquitous constituents of the gastrointestinal and oral microbiome …

Regulation of amino acid transport in Saccharomyces cerevisiae

F Bianchi, JS van't Klooster, SJ Ruiz… - … and Molecular Biology …, 2019 - Am Soc Microbiol
We review the mechanisms responsible for amino acid homeostasis in Saccharomyces
cerevisiae and other fungi. Amino acid homeostasis is essential for cell growth and survival …

Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence

RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …

Intravital imaging-based genetic screen reveals the transcriptional network governing Candida albicans filamentation during mammalian infection

RS Wakade, LC Ristow, M Wellington, DJ Krysan - Elife, 2023 - elifesciences.org
Candida albicans is one of the most common human fungal pathogens. C. albicans
pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically …

Fungal lifestyle reflected in serine protease repertoire

A Muszewska, MM Stepniewska-Dziubinska… - Scientific Reports, 2017 - nature.com
Fungi are able to switch between different lifestyles in order to adapt to environmental
changes. Their ecological strategy is connected to their secretome as fungi obtain nutrients …

Divergent Approaches to Virulence in C. albicans and C. glabrata: Two Sides of the Same Coin

M Galocha, P Pais, M Cavalheiro, D Pereira… - International journal of …, 2019 - mdpi.com
Candida albicans and Candida glabrata are the two most prevalent etiologic agents of
candidiasis worldwide. Although both are recognized as pathogenic, their choice of …

Fungal alterations in inflammatory bowel diseases

S Lam, T Zuo, M Ho, FKL Chan… - Alimentary …, 2019 - Wiley Online Library
Background Emerging data suggest that alterations in gut fungi may be associated with the
pathogenesis of inflammatory bowel disease (IBD). In healthy individuals, gut commensal …

Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections

MR Cruz, S Cristy, S Guha, GB De Cesare… - Nature …, 2022 - nature.com
Fungal pathogens are a continuing challenge due to few effective antifungals and a rise in
resistance. In previous work, we described the inhibition of Candida albicans virulence …