Macro‐and microvascular endothelial dysfunction in diabetes: 糖尿病诱导的内皮细胞功能损伤
Y Shi, PM Vanhoutte - Journal of diabetes, 2017 - Wiley Online Library
血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …
MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
SFRP2 improves mitochondrial dynamics and mitochondrial biogenesis, oxidative stress, and apoptosis in diabetic cardiomyopathy
T Ma, X Huang, H Zheng, G Huang, W Li… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. The mitochondrial dynamics and mitochondrial biogenesis are essential for
maintaining the bioenergy function of mitochondria in diabetic cardiomyopathy (DCM) …
maintaining the bioenergy function of mitochondria in diabetic cardiomyopathy (DCM) …
MicroRNA and ROS crosstalk in cardiac and pulmonary diseases
Reactive oxygen species (ROS) affect many cellular functions and the proper redox balance
between ROS and antioxidants contributes substantially to the physiological welfare of the …
between ROS and antioxidants contributes substantially to the physiological welfare of the …
Emerging roles for microRNAs in diabetic microvascular disease: novel targets for therapy
Y Zhang, X Sun, B Icli, MW Feinberg - Endocrinology Reviews, 2017 - academic.oup.com
Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …
[HTML][HTML] Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases
M Barteková, A Adameová, A Görbe… - Free Radical Biology …, 2021 - Elsevier
Cardiometabolic diseases (CMDs) are metabolic diseases (eg, obesity, diabetes,
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …
HIF-1, metabolism, and diabetes in the embryonic and adult heart
R Cerychova, G Pavlinkova - Frontiers in Endocrinology, 2018 - frontiersin.org
The heart is able to metabolize any substrate, depending on its availability, to satisfy its
energy requirements. Under normal physiological conditions, about 95% of ATP is produced …
energy requirements. Under normal physiological conditions, about 95% of ATP is produced …
Non‐coding RNA involvement in the pathogenesis of diabetic cardiomyopathy
W Zhang, W Xu, Y Feng, X Zhou - Journal of Cellular and …, 2019 - Wiley Online Library
In recent years, the incidence of diabetes has been increasing rapidly, which seriously
endangers human health. Diabetic cardiomyopathy, an important cardiovascular …
endangers human health. Diabetic cardiomyopathy, an important cardiovascular …
Mitochondrial mechanisms in diabetic cardiomyopathy
J Gollmer, A Zirlik, H Bugger - Diabetes & metabolism …, 2020 - synapse.koreamed.org
Mitochondrial medicine is increasingly discussed as a promising therapeutic approach,
given that mitochondrial defects are thought to contribute to many prevalent diseases and …
given that mitochondrial defects are thought to contribute to many prevalent diseases and …
What is the impact of ferroptosis on diabetic cardiomyopathy: a systematic review
X Lou, Y Zhang, J Guo, L Gao, Y Ding, X Zhuo… - Heart Failure …, 2024 - Springer
Iron overload increases the production of harmful reactive oxygen species in the Fenton
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …