Oral relugolix for androgen-deprivation therapy in advanced prostate cancer
Background Injectable luteinizing hormone–releasing hormone agonists (eg, leuprolide) are
the standard agents for achieving androgen deprivation for prostate cancer despite the initial …
the standard agents for achieving androgen deprivation for prostate cancer despite the initial …
Cardiovascular risks and toxicity-The Achilles heel of androgen deprivation therapy in prostate cancer patients
Androgen deprivation therapy (ADT) is the primary systemic therapy for treating locally
advanced or metastatic prostate cancer (PCa). Despite its positive effect on PCa patient …
advanced or metastatic prostate cancer (PCa). Despite its positive effect on PCa patient …
Stem cells as target for prostate cancer therapy: opportunities and challenges
C Escudero-Lourdes, I Alvarado-Morales… - Stem cell reviews and …, 2022 - Springer
Cancer stem cells (CSCs) and cells in a cancer stem cell-like (CSCL) state have proven to
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
be responsible for tumor initiation, growth, and relapse in Prostate Cancer (PCa) and other …
Metabolic consequences of gonadotropin‐releasing hormone agonists vs orchiectomy: a randomized clinical study
PB Østergren, C Kistorp, M Fode… - BJU …, 2019 - Wiley Online Library
Objectives To compare the metabolic changes between men with advanced prostate cancer
commenced on a gonadotropin‐releasing hormone (Gn RH) agonist and those treated with …
commenced on a gonadotropin‐releasing hormone (Gn RH) agonist and those treated with …
Follicle-stimulating hormone provokes macrophages to secrete IL-1β contributing to atherosclerosis progression
J Han, Y Song, W Yao, J Zhou, Y Du… - The Journal of …, 2023 - journals.aai.org
Abnormally high follicle-stimulating hormone (FSH) has been reported to associate with
cardiovascular diseases in prostate cancer patients with specific androgen deprivation …
cardiovascular diseases in prostate cancer patients with specific androgen deprivation …
Follicle-stimulating hormone exacerbates cardiovascular disease in the presence of low or castrate testosterone levels
WCM Duivenvoorden, D Margel… - Basic to Translational …, 2024 - jacc.org
Low testosterone (T), common in aging men, associates with cardiovascular disease. We
investigated whether follicle-stimulating hormone (FSH), which is affected by T, modulates …
investigated whether follicle-stimulating hormone (FSH), which is affected by T, modulates …
Cardio-oncology in advanced prostate cancer
Treatment intensification with androgen deprivation therapy (ADT) and androgen receptor
pathway inhibitors (ARPi) have led to improved survival in advanced prostate cancer …
pathway inhibitors (ARPi) have led to improved survival in advanced prostate cancer …
Surgical versus medical castration for metastatic prostate cancer: use and overall survival in a national cohort
AB Weiner, JE Cohen, JO DeLancey… - The Journal of …, 2020 - auajournals.org
Purpose: Surgical castration for metastatic prostate cancer is used less frequently than
medical castration yet costs less, requires less followup and may be associated with fewer …
medical castration yet costs less, requires less followup and may be associated with fewer …
Is androgen deprivation therapy for prostate cancer associated with cardiovascular disease? A meta‐analysis and systematic review
Z Liang, J Zhu, L Chen, Y Xu, Y Yang, R Hu… - …, 2020 - Wiley Online Library
Background Androgen deprivation therapy (ADT) is widely being applied in men who
suffered from prostate cancer. Whether androgen deprivation therapy (ADT) is associated …
suffered from prostate cancer. Whether androgen deprivation therapy (ADT) is associated …
Cardiovascular effects of androgen deprivation therapy in prostate cancer
M Agarwal, T Canan, G Glover, N Thareja… - Current oncology …, 2019 - Springer
Abstract Purpose of the Review This review paper is a comprehensive look at the
cardiovascular disease (CVD) risk that is associated with the use of androgen deprivation …
cardiovascular disease (CVD) risk that is associated with the use of androgen deprivation …