[HTML][HTML] Identification and validation of neurotrophic factor-related gene signatures in glioblastoma and Parkinson's disease
S Zhao, H Chi, Q Yang, S Chen, C Wu, G Lai… - Frontiers in …, 2023 - frontiersin.org
Background Glioblastoma multiforme (GBM) is the most common cancer of the central
nervous system, while Parkinson's disease (PD) is a degenerative neurological condition …
nervous system, while Parkinson's disease (PD) is a degenerative neurological condition …
Potential for stem cells therapy in Alzheimer's disease: do neurotrophic factors play critical role?
Alzheimer's disease (AD) is one of the most common causes of dementia. Despite several
decades of research in AD, there is no standard disease-modifying therapy available and …
decades of research in AD, there is no standard disease-modifying therapy available and …
[HTML][HTML] Alternative targets to fight Alzheimer's disease: focus on astrocytes
M Valenza, R Facchinetti, G Menegoni, L Steardo… - Biomolecules, 2021 - mdpi.com
The available treatments for patients affected by Alzheimer's disease (AD) are not curative.
Numerous clinical trials have failed during the past decades. Therefore, scientists need to …
Numerous clinical trials have failed during the past decades. Therefore, scientists need to …
Extracellular Vesicles Released from Neprilysin Gene‐Modified Human Umbilical Cord‐Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an …
HJ Jeong, OJ Kim, SH Oh, S Lee… - Stem cells …, 2021 - Wiley Online Library
Alzheimer's disease (AD) animal studies have reported that mesenchymal stem cells
(MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin …
(MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin …
[HTML][HTML] Therapeutic potential of dental pulp stem cell transplantation in a rat model of Alzheimer's disease
XM Zhang, YJ Ouyang, BQ Yu, W Li… - Neural regeneration …, 2021 - journals.lww.com
Dental pulp stem cells are dental pulp-derived mesenchymal stem cells that originate from
the neural crest. They exhibit greater potential for the treatment of nervous system diseases …
the neural crest. They exhibit greater potential for the treatment of nervous system diseases …
The effects of betulinic acid on neurobehavioral activity, electrophysiology and histological changes in an animal model of the Alzheimer's disease
Alzheimer's disease (AD) is a common disorder characterized by aggregation and
conversion of amyloid beta (Aβ) monomers to fibrils. Betulinic acid (BA) strongly accelerated …
conversion of amyloid beta (Aβ) monomers to fibrils. Betulinic acid (BA) strongly accelerated …
Effects of mesenchymal stem cells transplantation on cognitive deficits in animal models of Alzheimer's disease: A systematic review and meta‐analysis
M Ge, Y Zhang, Q Hao, Y Zhao, B Dong - Brain and behavior, 2018 - Wiley Online Library
Background Alzheimer's disease (AD) is a globally prevalent neurodegenerative disease,
clinically characterized by progressive memory loss and gradual impairment of cognitive …
clinically characterized by progressive memory loss and gradual impairment of cognitive …
Lindera glauca Blume ameliorates amyloid-β1-42-induced memory impairment in mice with neuroprotection and activation of the CREB-BDNF pathway
Y Kim, SH Cho - Neurochemistry International, 2021 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disorder presenting cognitive
decline accompanied by deposits of amyloid-β (Aβ) and tau hyperphosphorylation. Without …
decline accompanied by deposits of amyloid-β (Aβ) and tau hyperphosphorylation. Without …
Neurotrophic factors mediated activation of astrocytes ameliorate memory loss by amyloid clearance after transplantation of lineage negative stem cells
Alzheimer's disease (AD) is one of the untreatable neurodegenerative disorders with
associated societal burden. Current therapies only provide symptomatic relief without …
associated societal burden. Current therapies only provide symptomatic relief without …
[HTML][HTML] Short-lived human umbilical cord-blood-derived neural stem cells influence the endogenous secretome and increase the number of endogenous neural …
A Jablonska, K Drela, L Wojcik-Stanaszek… - Molecular …, 2016 - Springer
Stroke is the leading cause of severe disability, and lacunar stroke is related to cognitive
decline and hemiparesis. There is no effective treatment for the majority of patients with …
decline and hemiparesis. There is no effective treatment for the majority of patients with …