The incidence of many types of cancer arising in organs with non-reproductive functions is
significantly higher in male populations than in female populations, with associated …

Normal and neoplastic growth of the prostate gland are dependent on androgen receptor
(AR) expression and function. Androgenic activation of the AR, in association with its …

The newborn immune system is characterized by an impaired Th1-associated immune
response. Hepatitis B virus (HBV) transmitted from infected mothers to newborns is thought …

Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive genetic disorder
resulting from maternally inherited or de novo mutations involving the androgen receptor …

The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

SOX9 is a member of the SOX [S ry-related high-mobility group (HMG) b ox] family of HMG
DNA-binding domain transcription factors and is required for the development and …

Male-specific reproductive disorders and cancers have increased intensely in recent years,
making them a significant public health problem. Prostate cancer (PC) is the most often …

The NKX3. 1 homeobox gene plays essential roles in prostate differentiation and prostate
cancer. We show that loss of function of Nkx3. 1 in mouse prostate results in down …

The gonadoblastoma (GBY) locus is the only oncogenic locus on the human Y chromosome.
It is postulated to serve a normal function in the testis, but could exert oncogenic effects in …

The human AT-rich interaction domain (ARID) family contains seven subfamilies and 15
members characterized by having an ARID. Members of the ARID family have the ability to …