Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

Over the past decade, myocardial structure, cardiomyocyte function, and intramyocardial
signaling were shown to be specifically altered in heart failure with preserved ejection …

Aims Apnoea–hypopnoea index (AHI), the universal clinical metric of sleep apnoea severity,
poorly predicts the adverse outcomes of sleep apnoea, potentially because the AHI, a …

Objectives: This study evaluated the associations of obesity and cardiometabolic traits with
incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF) …

Sodium glucose cotransporter 2 inhibitors (SGLT2i) constitute a promising drug treatment for
heart failure patients with either preserved or reduced ejection fraction. Whereas SGLT2i …

Obstructive sleep apnea (OSA) is an underdiagnosed condition characterized by recurrent
episodes of obstruction of the upper airway leading to sleep fragmentation and intermittent …

Context Systemic hypertension is prevalent among patients with obstructive sleep apnea
(OSA). Short-term studies indicate that continuous positive airway pressure (CPAP) therapy …

Obesity represents a major risk factor for a plethora of severe diseases, including diabetes,
cardiovascular disease, non-alcoholic fatty liver disease, and cancer. It is often …

Obstructive sleep apnea syndrome (OSAS) is characterized by intermittent hypoxia (IH)
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …

Obstructive sleep apnea (OSA) is characterized by repetitive apnea–hypopnea cycles
during sleep, which are associated with oxygen desaturation and sleep disruption. Up to …