Disease overview Chronic lymphocytic leukemia (CLL) is one of the most frequent types of
leukemia. It typically occurs in elderly patients and has a highly variable clinical course …

Abstract Disease Overview Chronic lymphocytic leukemia (CLL) is the commonest leukemia
in western countries. The disease typically occurs in elderly patients and has a highly …

Disease overview Chronic lymphocytic leukemia (CLL) is the commonest leukemia in
western countries. The disease typically occurs in elderly patients and has a highly variable …

Although T cells expressing CD19-specific chimeric antigen receptors (CARs) are a
promising new therapy for B-cell malignancies, objective responses are observed at lower …

Disease overview: Chronic lymphocytic leukemia (CLL) is the commonest leukemia in
western countries. The disease typically occurs in elderly patients and has a highly variable …

Combination chemotherapy with fludarabine plus cyclophosphamide (FC) was compared
with the standard regimen of fludarabine monotherapy in first-line treatment of younger …

Purpose The combination of fludarabine and cyclophosphamide is an effective regimen for
patients with chronic lymphocytic leukemia (CLL). However, it may be accompanied by …

Rituximab is a chimeric monoclonal antibody directed at CD20 with significant activity in non-
Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). A variety of pathways of …

Disease Overview: Chronic lymphocytic leukemia (CLL) is the commonest leukemia in
western countries. The disease typically occurs in elderly patients and has a highly variable …

The MCL1 gene (myeloid cell leukemia-1) was discovered serendipitously about a decade
ago and proved to be a member of the emerging BCL2 gene family. Ongoing studies of this …