Hemorrhagic shock

JW Cannon - New England Journal of Medicine, 2018 - Mass Medical Soc
Hemorrhagic Shock | New England Journal of Medicine Skip to main content Access provided
byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine homepage …

The far-reaching scope of neuroinflammation after traumatic brain injury

DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

Transfusion of plasma, platelets, and red blood cells in a 1: 1: 1 vs a 1: 1: 2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial

JB Holcomb, BC Tilley, S Baraniuk, EE Fox, CE Wade… - Jama, 2015 - jamanetwork.com
Importance Severely injured patients experiencing hemorrhagic shock often require massive
transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red …

Association of prehospital blood product transfusion during medical evacuation of combat casualties in Afghanistan with acute and 30-day survival

SA Shackelford, DJ Del Junco, N Powell-Dunford… - Jama, 2017 - jamanetwork.com
Importance Prehospital blood product transfusion in trauma care remains controversial due
to poor-quality evidence and cost. Sequential expansion of blood transfusion capability after …

Goal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional …

E Gonzalez, EE Moore, HB Moore… - Annals of …, 2016 - journals.lww.com
Background: Massive transfusion protocols (MTPs) have become standard of care in the
management of bleeding injured patients, yet strategies to guide them vary widely. We …

Trauma-induced coagulopathy

EE Moore, HB Moore, LZ Kornblith, MD Neal… - Nature reviews Disease …, 2021 - nature.com
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

Outcome prediction in patients with severe traumatic brain injury using deep learning from head CT scans

M Pease, D Arefan, J Barber, E Yuh, A Puccio… - Radiology, 2022 - pubs.rsna.org
Background After severe traumatic brain injury (sTBI), physicians use long-term
prognostication to guide acute clinical care yet struggle to predict outcomes in comatose …

Trends in 1029 trauma deaths at a level 1 trauma center: impact of a bleeding control bundle of care

BT Oyeniyi, EE Fox, M Scerbo, JS Tomasek, CE Wade… - Injury, 2017 - Elsevier
Background Over the last decade the age of trauma patients and injury mortality has
increased. At the same time, many centers have implemented multiple interventions focused …

Evidence-based and clinically relevant outcomes for hemorrhage control trauma trials

JB Holcomb, EE Moore, JL Sperry, JO Jansen… - Annals of …, 2021 - journals.lww.com
Objective: To address the clinical and regulatory challenges of optimal primary endpoints for
bleeding patients by developing consensus-based recommendations for primary clinical …

Traumatic hemorrhage and chain of survival

RK Latif, SP Clifford, JA Baker, R Lenhardt… - Scandinavian Journal of …, 2023 - Springer
Trauma is the number one cause of death among Americans between the ages of 1 and 46
years, costing more than $670 billion a year. Following death related to central nervous …