Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system

K Leisegang, R Henkel… - American journal of …, 2019 - Wiley Online Library
Obesity and metabolic syndrome (MetS) are global epidemics, driven by an obesogenic
environment. This is mediated by complex underlying pathophysiology, in which chronic …

Effects of alpha lipoic acid on metabolic syndrome: A comprehensive review

N Najafi, S Mehri… - Phytotherapy …, 2022 - Wiley Online Library
Metabolic syndrome (MetS) is a multifactorial disease with medical conditions such as
hypertension, diabetes, obesity, dyslipidemia, and insulin resistance. Alpha‐lipoic acid (α …

The effect of 600 mg alpha‐lipoic acid supplementation on oxidative stress, inflammation, and RAGE in older adults with type 2 diabetes mellitus

VM Mendoza-Núñez, BI García-Martínez… - Oxidative medicine …, 2019 - Wiley Online Library
Alpha‐lipoic acid (ALA) has been used as a dietary supplement at different doses in patients
with diabetes mellitus type 2 (T2DM) due to its antioxidant, anti‐inflammatory, and …

[HTML][HTML] Mechanics insights of alpha-lipoic acid against cardiovascular diseases during COVID-19 infection

L Rochette, S Ghibu - International Journal of Molecular Sciences, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in late December
2019. Since then, COVID-19 has spread rapidly worldwide and was declared a global …

The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis …

M Akbari, V Ostadmohammadi, KB Lankarani, R Tabrizi… - Metabolism, 2018 - Elsevier
Objective This systematic review and meta-analysis of randomized controlled trials (RCTs)
was performed to summarize the effect of alpha-lipoic acid (ALA) supplementation on …

Alpha‐Lipoic Acid, Auraptene, and Particularly Their Combination Prevent the Metastasis of U87 Human Glioblastoma Cells

A Izadi, M Soukhtanloo, F Mirzavi… - Evidence‐Based …, 2023 - Wiley Online Library
Background. The primary malignant brain tumor glioblastoma multiforme (GBM) is most
commonly detected in individuals over 60 years old. The standard therapeutic approach for …

Are reactive sulfur species the new reactive oxygen species?

KR Olson - Antioxidants & Redox Signaling, 2020 - liebertpub.com
Significance: Oxidative stress in moderation positively affects homeostasis through
signaling, while in excess it is associated with adverse health outcomes. Both activities are …

The effect of alpha-lipoic acid on inflammatory mediators: a systematic review and meta-analysis on randomized clinical trials

F Haghighatdoost, M Hariri - European journal of pharmacology, 2019 - Elsevier
Abstract Alpha-Lipoic Acid (ALA) is a natural antioxidant compound which is naturally found
in plant sources. New evidence revealed that ALA can reduce inflammation. Our objective in …

[HTML][HTML] Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

X Zhang, C Xue, Q Xu, Y Zhang, H Li, F Li, Y Liu… - Nutrition & …, 2019 - Springer
Background As reported previously by our group, medium-chain triglycerides can ameliorate
atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized …

[HTML][HTML] The beneficial effect of Alpha-lipoic acid supplementation as a potential adjunct treatment in episodic migraines

MR Kelishadi, AA Naeini, F Khorvash, G Askari… - Scientific reports, 2022 - nature.com
The current study was performed to evaluate the effects of alpha-lipoic acid (ALA)
supplementation on lactate, nitric oxide (NO), vascular cell adhesion molecule-1 (VCAM-1) …