Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

A review on endocrine disruptors and their possible impacts on human health

ER Kabir, MS Rahman, I Rahman - Environmental toxicology and …, 2015 - Elsevier
Endocrine disruption is a named field of research which has been very active for over 10
years, although the effects of endocrine disruptors in wildlife have been studied mainly in …

Environmental pollution and health hazards from distillery wastewater and treatment approaches to combat the environmental threats: a review

P Chowdhary, A Raj, RN Bharagava - Chemosphere, 2018 - Elsevier
Distillery industries are the key contributor to the world's economy, but these are also one of
the major sources of environmental pollution due to the discharge of a huge volume of dark …

Environmental obesogens: mechanisms and controversies

JJ Heindel, B Blumberg - Annual review of pharmacology and …, 2019 - annualreviews.org
Obesity is a worldwide pandemic in adults as well as children and adds greatly to health
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …

The regulation of endocrine-disrupting chemicals to minimize their impact on health

C Duh-Leong, MV Maffini, CD Kassotis… - Nature Reviews …, 2023 - nature.com
Endocrine-disrupting chemicals (EDCs) are substances generated by human industrial
activities that are detrimental to human health through their effects on the endocrine system …

Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations

M Manikkam, R Tracey, C Guerrero-Bosagna… - PloS one, 2013 - journals.plos.org
Environmental compounds are known to promote epigenetic transgenerational inheritance
of adult onset disease in subsequent generations (F1–F3) following ancestral exposure …