The kallikrein-kinin and the renin-angiotensin systems have a multilayered interaction

AH Schmaier - American Journal of Physiology-Regulatory …, 2003 - journals.physiology.org
Understanding the physiological role of the plasma kallikrein-kinin system (KKS) has been
hampered by not knowing how the proteins of this proteolytic system, when assembled in …

Renin, genes, microRNAs, and renal mechanisms involved in hypertension

BJ Morris - Hypertension, 2015 - Am Heart Assoc
Morris Renin, Genes, MicroRNAs, Kidney, Hypertension 957 resting conditions, but
expression could be switched on by low sodium diet and angiotensin-converting enzyme …

The contact activation system: biochemistry and interactions of these surface-mediated defense reactions

RW Colman, AH Schmaier, OD Ratnoff - Critical Reviews in Oncology …, 1986 - Elsevier
Five proteins, namely, factor XII (Hageman factor), prekallikrein (Flelchcr factor), htctor XI
(plasma thromboplastin antecedent [PTAJ), high molecular weight kininogen …

Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system

N Biswas, AX Maihofer, SA Mir, F Rao, K Zhang… - BMC medical …, 2016 - Springer
Abstract Background Plasma coagulation Factor XIIa (Hageman factor; encoded by F12)
and kallikrein (KAL or Fletcher factor; encoded by KLKB1) are proteases of the kallikerin …

[PDF][PDF] New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated

BJ Morris - Clin Sci, 1986 - researchgate.net
The recent determination of the structure of the human renin gene [1-7](described most
cornpletely in [4]) provides a wealth of basic essential information from which much insight …

Human renin protein and gene structures: present and future targets for renin blockade in treatment of hypertension

BJ Morris - Journal of Hypertension, 1989 - journals.lww.com
The cloning of the gene for human renin has permitted remarkable advances to be made in
understanding the structure of this aspartyl protease. From computer models and the …

Renin: from 'pro'to promoter

BJ Morris - BioEssays, 2003 - Wiley Online Library
Renin is the rate‐limiting enzyme in a cascade that leads to production of angiotensin II,
which is perhaps our most important regulator of salt and water balance and blood pressure …

Activation by puff adder venom of inactive renin in normal and hypertensive rat plasma

BJ Morris, JE Taylor - Clinical and experimental pharmacology …, 1987 - Wiley Online Library
Inactive renin has been studied extensively in human plasma, but in animal plasma its
accurate quantification has proved more difficult, due partly to higher activity of plasma …

Renin, genes, and beyond: 40 years of molecular discoveries in the hypertension field

BJ Morris - 2011 - Am Heart Assoc
Little did I know when I attended the Council for High Blood Pressure Research meeting in
Cleveland, Ohio in 1975 when Lewis K. Dahl received the major award for demonstrating …

[PDF][PDF] Lewis K. Dahl Memorial Lecture

BJ Morris - Hypertension, 2011 - Citeseer
Little did I know when I attended the Council for High Blood Pressure Research meeting in
Cleveland, Ohio in 1975 when Lewis K. Dahl received the major award for demonstrating …