Biomechanics of collective cell migration in cancer progression: experimental and computational methods

CP Spatarelu, H Zhang, DT Nguyen… - ACS biomaterials …, 2019 - ACS Publications
Cell migration is essential for regulating many biological processes in physiological or
pathological conditions, including embryonic development and cancer invasion. In vitro and …

Generation, transmission, and regulation of mechanical forces in embryonic morphogenesis

J Sutlive, H Xiu, Y Chen, K Gou, F Xiong, M Guo… - Small, 2022 - Wiley Online Library
Embryonic morphogenesis is a biological process which depicts shape forming of tissues
and organs during development. Unveiling the roles of mechanical forces generated …

Realization of polaritonic topological charge at room temperature using polariton bound states in the continuum from perovskite metasurface

NHM Dang, S Zanotti, E Drouard… - Advanced Optical …, 2022 - Wiley Online Library
Exciton‐polaritons are mixed light–matter excitations resulting from the strong coupling
regime between an active excitonic material and photonic resonances. Harnessing these …

On the determination of elastic moduli of cells by AFM based indentation

Y Ding, GK Xu, GF Wang - Scientific reports, 2017 - nature.com
The atomic force microscopy (AFM) has been widely used to measure the mechanical
properties of biological cells through indentations. In most of existing studies, the cell is …

Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions

X Yue, TD Nguyen, V Zellmer, S Zhang, P Zorlutuna - Biomaterials, 2018 - Elsevier
Tumor properties such as growth and metastasis are dramatically dependent on the tumor
microenvironment (TME). However, the diversity of the TME including the stiffness and the …

3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth

J Casey, X Yue, TD Nguyen, A Acun… - Biomedical …, 2017 - iopscience.iop.org
The tumor microenvironment (TME) is distinctly heterogeneous and is involved in tumor
growth, metastasis, and drug resistance. Mimicking this diverse microenvironment is …

Enhancing interconnect reliability and performance by converting tantalum to 2D layered tantalum sulfide at low temperature

CL Lo, M Catalano, A Khosravi, W Ge, Y Ji… - Advanced …, 2019 - Wiley Online Library
The interconnect half‐pitch size will reach≈ 20 nm in the coming sub‐5 nm technology
node. Meanwhile, the TaN/Ta (barrier/liner) bilayer stack has to be> 4 nm to ensure …

Investigation of red blood cell mechanical properties using AFM indentation and coarse-grained particle method

S Barns, MA Balanant, E Sauret, R Flower… - Biomedical engineering …, 2017 - Springer
Abstract Background Red blood cells (RBCs) deform significantly and repeatedly when
passing through narrow capillaries and delivering dioxygen throughout the body …

Impact of nanoparticle uptake on the biophysical properties of cell for biomedical engineering applications

MAI Rasel, S Singh, TD Nguyen, IO Afara, Y Gu - Scientific Reports, 2019 - nature.com
Nanomaterials are currently the state-of-the-art in the development of advanced biomedical
devices and applications where classical approaches have failed. To date, majority of the …

Investigation of cell-substrate adhesion properties of living chondrocyte by measuring adhesive shear force and detachment using AFM and inverse FEA

TD Nguyen, YT Gu - Scientific reports, 2016 - nature.com
It is well-known that cell adhesion is important in many biological processes such as cell
migration and proliferation. A better understanding of the cell adhesion process will shed …