The number of cancer-related diseases is still growing. Despite the availability of a large
number of anticancer drugs, the ideal drug is still being sought that would be effective …

Glycans and their glycoconjugates are complex biomolecules that are crucial for various
biological processes. Glycoconjugates are found in all domains of life. They are covalently …

Background Hypoxia is associated with the development of pancreatic cancer (PC).
However, genes associated with hypoxia response and their regulatory mechanism in PC …

Mantle cell lymphoma (MCL) is an incurable B-cell neoplasm characterized by an
aggressive behavior, short responses to conventional therapies and SOX11 overexpression …

Methotrexate (MTX) is a commonly used antimetabolite, which inhibits folate and DNA
synthesis to be effective in the treatment of various malignancies. However, MTX therapy is …

The side effects of small molecule chemotherapeutic drugs (SMCD) have brought great pain
to the cancer patients. Many nanodrug carriers can relieve the shortcomings of SMCD, but …

Smart nanotechnology has revolutionized the arena of therapeutics and their delivery as
well as diagnostics. It is an advancing field, wherein the “smart” nanoparticles respond to a …

Patients with hematologic malignancies require intensive therapies, including high-dose
chemotherapy. Antimetabolite–methotrexate (MTX) has been used for many years in the …

Mantle cell lymphoma (MCL) is an incurable B-cell neoplasm characterized by its
aggressive behavior, short responses to conventional therapies and SOX11 overexpression …

Background Hypoxia participated in the occurrence and development of pancreatic cancer
(PC). However, genes associated with hypoxia respond and their regulated mechanism in …