1, 2, 4-Oxadiazole is an essential motif in drug discovery represented in many experimental,
investigational, and marketed drugs. This review covers synthetic methods that allow the …

Owing to the mild generation methods, arynes have been widely used in synthetic chemistry.
However, achieving asymmetric organocatalytic reactions with arynes remains a formidable …

Nucleophilic ionic sources of fluoride are essential reagents in the synthetic toolbox to
access high added-value fluorinated building blocks unattainable by other means. In this …

A Cu (II) fluoride-catalyzed N-arylation of 7-azaindole N-oxides (7-AINO) has been
developed using boronic acid under base-free conditions. During the process, a …

The increased synthetic utility of organosilanes has motivated researchers to develop milder
and more practical synthetic methods. Silylzinc reagents, which are typically the most …

New thiosemicarbazide-linked acridines 3a–c were prepared and investigated as
chemosensors for the detection of biologically and environmentally important anions. The …

The asymmetric nucleophilic catalysis by fluoride ions at a carbon-based electrophile has
been demonstrated for the first time. Using a library of ad hoc designed bifunctional phase …

We disclose a pair of ortho-sulfinylaniline auxiliaries for palladium-catalyzed β–CH arylation
of alkyl carboxamides. Together, these auxiliaries offer a means to effect efficient β-methyl …

We serendipitously found an unprecedented 5-to-7-membered ring expansion of 2-
alkylspiroindolenines to azepinoindoles mediated by n-tetrabutylammonium fluoride. The …

The possibility of fluoride-mediated selective dephosphonylation of α-diazo-β-carbonyl
phosphonates such as the Ohira–Bestmann reagent has been proposed and executed. The …