Much evidence shows that physical exercise (PE) is a strong gene modulator that induces
structural and functional changes in the brain, determining enormous benefit on both …

A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

There is growing evidence that the preconceptual lifestyle and other environmental
exposures of a father can significantly alter the physiological and behavioral phenotypes of …

Multiple studies have demonstrated an association between cigarette smoking and
increased anxiety symptoms or disorders, with early life exposures potentially predisposing …

Obesity is now a worldwide epidemic. In recent years, different phenotypes of obesity,
ranging from metabolically healthy normal weight to metabolically unhealthy obese, were …

Epigenetics is the study of gene expression changes that occur in the absence of altered
genotype. Current evidence indicates a role for environmentally induced alterations to …

Alzheimer's disease (AD) is associated with increased depression-related behaviours.
Previous studies have reported a greater risk of AD and depression in women. In recent …

Clinical evidence has shown that physical exercise during pregnancy may alter brain
development and improve cognitive function of offspring. However, the mechanisms through …

Age-related neurodegenerative disorders such as Alzheimer's disease (AD) have become a
critical public health issue due to the significantly extended human lifespan, leading to …

Fetal exposure to general anesthetics may pose significant neurocognitive risks but methods
to mitigate against these detrimental effects are still to be determined. We set out, therefore …