Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation
N Germic, Z Frangez, S Yousefi… - Cell Death & Differentiation, 2019 - nature.com
Autophagy is well equipped functionally to isolate microbial pathogens in autophagosomes
and to carry out their clearance by dismemberment in the course of catabolic processes in …
and to carry out their clearance by dismemberment in the course of catabolic processes in …
Autophagy and inflammation
Y Matsuzawa-Ishimoto, S Hwang… - Annual review of …, 2018 - annualreviews.org
The cellular degradative pathway of autophagy has a fundamental role in immunity. Here,
we review the function of autophagy and autophagy proteins in inflammation. We discuss …
we review the function of autophagy and autophagy proteins in inflammation. We discuss …
A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Pancreatic cancers require autophagy for tumor growth
Macroautophagy (autophagy) is a regulated catabolic pathway to degrade cellular
organelles and macromolecules. The role of autophagy in cancer is complex and may differ …
organelles and macromolecules. The role of autophagy in cancer is complex and may differ …
Regulation of mammalian autophagy in physiology and pathophysiology
(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …
proteins and organelles. Autophagy is initiated by double-membraned structures, which …
Microautophagy of cytosolic proteins by late endosomes
Autophagy delivers cytosolic components to lysosomes for their degradation. The delivery of
autophagic cargo to late endosomes for complete or partial degradation has also been …
autophagic cargo to late endosomes for complete or partial degradation has also been …
Functions of autophagy in normal and diseased liver
Autophagy has emerged as a critical lysosomal pathway that maintains cell function and
survival through the degradation of cellular components such as organelles and proteins …
survival through the degradation of cellular components such as organelles and proteins …
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
N Mizushima, A Yamamoto, M Matsui… - Molecular biology of …, 2004 - Am Soc Cell Biol
Macroautophagy mediates the bulk degradation of cytoplasmic components. It accounts for
the degradation of most long-lived proteins: cytoplasmic constituents, including organelles …
the degradation of most long-lived proteins: cytoplasmic constituents, including organelles …
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
R Cooney, J Baker, O Brain, B Danis, T Pichulik… - Nature medicine, 2010 - nature.com
Nucleotide-binding oligomerization domain–containing-2 (NOD2) acts as a bacterial sensor
in dendritic cells (DCs), but it is not clear how bacterial recognition links with antigen …
in dendritic cells (DCs), but it is not clear how bacterial recognition links with antigen …