[HTML][HTML] Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

[HTML][HTML] IL-17 and IL-17-producing cells in protection versus pathology

KHG Mills - Nature Reviews Immunology, 2023 - nature.com
IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

Hidradenitis suppurativa

R Sabat, GBE Jemec, Ł Matusiak, AB Kimball… - Nature Reviews …, 2020 - nature.com
Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …

[HTML][HTML] The IL-23/IL-17 pathway in inflammatory skin diseases: from bench to bedside

T Liu, S Li, S Ying, S Tang, Y Ding, Y Li, J Qiao… - Frontiers in …, 2020 - frontiersin.org
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …

Hidradenitis suppurativa: epidemiology, clinical presentation, and pathogenesis

SR Goldburg, BE Strober, MJ Payette - Journal of the American Academy …, 2020 - Elsevier
Hidradenitis suppurativa (HS) is an inflammatory disorder that is characterized by chronic
deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in the axilla, inguinal area …

What causes hidradenitis suppurativa?—15 years after

CC Zouboulis, F Benhadou, AS Byrd… - Experimental …, 2020 - Wiley Online Library
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …

Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project

A Garg, E Neuren, D Cha, JS Kirby, JR Ingram… - Journal of the American …, 2020 - Elsevier
Background A needs assessment for patients with hidradenitis suppurativa (HS) will support
advancements in multidisciplinary care, treatment, research, advocacy, and philanthropy …

[HTML][HTML] Hidradenitis suppurativa: a systematic review integrating inflammatory pathways into a cohesive pathogenic model

ARJV Vossen, HH Van der Zee, EP Prens - Frontiers in immunology, 2018 - frontiersin.org
Background: The pathogenesis of hidradenitis suppurativa (HS) is not fully understood. This
systematic review examined the latest evidence for molecular inflammatory pathways …

[HTML][HTML] IL-17A in psoriasis and beyond: cardiovascular and metabolic implications

E von Stebut, WH Boehncke, K Ghoreschi… - Frontiers in …, 2020 - frontiersin.org
Interleukin 17A (IL-17A) is one of the currently known six members of the IL-17 cytokine
family and is implicated in immune responses to infectious pathogens and in the …

[HTML][HTML] T cell pathology in skin inflammation

R Sabat, K Wolk, L Loyal, WD Döcke… - Seminars in …, 2019 - Springer
Forming the outer body barrier, our skin is permanently exposed to pathogens and
environmental hazards. Therefore, skin diseases are among the most common disorders. In …