Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury
AJ Ghio, JM Soukup, LA Dailey, MC Madden - Free Radical Biology and …, 2020 - Elsevier
Air pollutants cause changes in iron homeostasis through: 1) a capacity of the pollutant, or a
metabolite (s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the …
metabolite (s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the …
Epigenetic impacts of maternal tobacco and e-vapour exposure on the offspring lung
In utero exposure to tobacco products, whether maternal or environmental, have harmful
effects on first neonatal and later adult respiratory outcomes. These effects have been …
effects on first neonatal and later adult respiratory outcomes. These effects have been …
Environmentally persistent free radicals: Methods for combustion generation, whole-body inhalation and assessing cardiopulmonary consequences
Particulate matter (PM) containing environmentally persistent free radicals (EPFRs) results
from the incomplete combustion of organic wastes which chemisorb to transition metals. This …
from the incomplete combustion of organic wastes which chemisorb to transition metals. This …
[HTML][HTML] In utero exposures to electronic-cigarette aerosols impair the Wnt signaling during mouse lung development
A Noël, S Hansen, A Zaman… - … of Physiology-Lung …, 2020 - journals.physiology.org
Currently, more than 9 million American adults, including women of childbearing age, use
electronic-cigarettes (e-cigs). Further, the prevalence of maternal vaping now approaching …
electronic-cigarettes (e-cigs). Further, the prevalence of maternal vaping now approaching …
[HTML][HTML] In utero exposures to mint-flavored JUUL aerosol impair lung development and aggravate house dust mite-induced asthma in adult offspring mice
KM Cahill, TK Johnson, Z Perveen, M Schexnayder… - Toxicology, 2022 - Elsevier
There are few reports concerning electronic nicotine delivery system (ENDS) use during
pregnancy and no studies on asthma in prenatally JUUL-exposed offspring. Here, we tested …
pregnancy and no studies on asthma in prenatally JUUL-exposed offspring. Here, we tested …
Inhalation of particulate matter containing free radicals leads to decreased vascular responsiveness associated with an altered pulmonary function
AC Harmon, A Noël, B Subramanian… - American Journal …, 2021 - journals.physiology.org
Airborne particulate matter (PM) is associated with an increased risk for cardiovascular
diseases. Although the goal of thermal remediation is to eliminate organic wastes through …
diseases. Although the goal of thermal remediation is to eliminate organic wastes through …
Mmp12 Is Upregulated by in utero Second-Hand Smoke Exposures and Is a Key Factor Contributing to Aggravated Lung Responses in Adult Emphysema, Asthma …
A Noël, Z Perveen, R Xiao, H Hammond… - Frontiers in …, 2021 - frontiersin.org
Matrix metalloproteinase-12 (Mmp12) is upregulated by cigarette smoke (CS) and plays a
critical role in extracellular matrix remodeling, a key mechanism involved in physiological …
critical role in extracellular matrix remodeling, a key mechanism involved in physiological …
Early-life exposure to cigarette smoke primes lung function and DNA methylation changes at Cyp1a1 upon exposure later in life
CD Onuzulu, S Lee, S Basu, J Comte… - … of Physiology-Lung …, 2023 - journals.physiology.org
Prenatal and early-life exposure to cigarette smoke (CS) has repeatedly been shown to
induce stable, long-term changes in DNA methylation (DNAm) in offspring. It has been …
induce stable, long-term changes in DNA methylation (DNAm) in offspring. It has been …
Sex-specific lung functional changes in adult mice exposed only to second-hand smoke in utero
A Noël, R Xiao, Z Perveen, H Zaman, V Le Donne… - Respiratory …, 2017 - Springer
Background An increasing number of epidemiological and experimental studies have
associated exposure to second-hand smoke (SHS) during pregnancy with adverse …
associated exposure to second-hand smoke (SHS) during pregnancy with adverse …
In utero and early-life exposure to thirdhand smoke causes profound changes to the immune system
AM Snijders, M Zhou, TP Whitehead, B Fitch… - Clinical …, 2021 - portlandpress.com
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Thirdhand
smoke (THS) is the residual tobacco contamination that remains after the smoke clears. We …
smoke (THS) is the residual tobacco contamination that remains after the smoke clears. We …