Plastids and mitochondria are the only organelles that possess genomes of endosymbiotic
origin. In recent decades, advances in sequencing technologies have contributed to a …

The mitochondria contain their own genome derived from an alphaproteobacterial
endosymbiont. From thousands of protein-coding genes originally encoded by their …

Nuclear and organellar genomes can evolve at vastly different rates despite occupying the
same cell. In most bilaterian animals, mitochondrial DNA (mtDNA) evolves faster than …

There is remarkable variation in the rate at which genetic incompatibilities in molecular
interactions accumulate. In some cases, minor changes—even single-nucleotide …

Eukaryotic nuclear genomes often encode distinct sets of translation machinery for function
in the cytosol vs. organelles (mitochondria and plastids). This raises questions about why …

The angiosperm genus Silene has been the subject of extensive study in the field of ecology
and evolution, but the availability of high-quality reference genome sequences has been …

Eukaryotes maintain separate protein translation systems for nuclear and organellar genes,
including distinct sets of tRNAs and aminoacyl-tRNA synthetases (aaRSs). In animals …

Across eukaryotes, most genes required for mitochondrial function have been transferred to,
or otherwise acquired by, the nucleus. Encoding genes in the nucleus has many …

Metabolic dysfunction associated steatotic liver disease (MASLD) is a worldwide problem,
affecting more than 20% of the population. As poor diet and sedentary lifestyles become …

Eukaryotic nuclear genomes often encode distinct sets of protein translation machinery for
function in the cytosol vs. organelles (mitochondria and plastids). This phenomenon raises …