Predictors of mortality in patients with drug-resistant tuberculosis: A systematic review and meta-analysis

A Alemu, ZW Bitew, T Worku, DF Gamtesa, A Alebel - PLoS One, 2021 - journals.plos.org
Background Even though the lives of millions have been saved in the past decades, the
mortality rate in patients with drug-resistant tuberculosis is still high. Different factors are …

Comorbidities and treatment outcomes in multidrug resistant tuberculosis: a systematic review and meta-analysis

JP Samuels, A Sood, JR Campbell, F Ahmad Khan… - Scientific reports, 2018 - nature.com
Little is known about the impact of comorbidities on multidrug resistant (MDR) and
extensively drug resistant (XDR) tuberculosis (TB) treatment outcomes. We aimed to …

Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra

DX Ji, LH Yamashiro, KJ Chen, N Mukaida… - Nature …, 2019 - nature.com
Abstract The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis and is
responsible for more human mortality than any other single pathogen. Progression to active …

Multidrug-resistant tuberculosis treatment outcomes in relation to treatment and initial versus acquired second-line drug resistance

JP Cegielski, E Kurbatova… - Clinical Infectious …, 2016 - academic.oup.com
Background. Resistance to second-line drugs develops during treatment of multidrug-
resistant (MDR) tuberculosis, but the impact on treatment outcome has not been determined …

Gyrase mutations are associated with variable levels of fluoroquinolone resistance in Mycobacterium tuberculosis

MR Farhat, KR Jacobson, MF Franke… - Journal of clinical …, 2016 - Am Soc Microbiol
Molecular diagnostics that rapidly and accurately predict resistance to fluoroquinolone drugs
and especially later-generation agents promise to improve treatment outcomes for patients …

[HTML][HTML] Treatment outcomes of drug resistant tuberculosis patients with multiple poor prognostic indicators in Uganda: a countrywide 5-year retrospective study

JB Baluku, B Nakazibwe, J Naloka, M Nabwana… - Journal of clinical …, 2021 - Elsevier
Background Comorbid conditions and adverse drug events are associated with poor
treatment outcomes among patients with drug resistant tuberculosis (DR–TB). This study …

[HTML][HTML] Poor treatment outcome and its predictors among drug-resistant tuberculosis patients in Ethiopia: a systematic review and meta-analysis

A Alemu, ZW Bitew, T Worku - International Journal of Infectious Diseases, 2020 - Elsevier
Objective To assess poor treatment outcomes and their predictors among drug-resistant
tuberculosis patients treated in Ethiopia. Methods Data were searched from both electronic …

Risk factors for poor multidrug-resistant tuberculosis treatment outcomes in Kyiv Oblast, Ukraine

O Aibana, M Bachmaha, V Krasiuk, N Rybak… - BMC infectious …, 2017 - Springer
Background Ukraine is among ten countries with the highest burden of multidrug-resistant
TB (MDR-TB) worldwide. Treatment success rates for MDR-TB in Ukraine remain below …

Management and treatment outcomes of MDR-TB: results from a setting with high rates of drug resistance

N Ahmad, A Javaid, A Basit, AK Afridi… - … of Tuberculosis and …, 2015 - ingentaconnect.com
SETTINGS: Although Pakistan has a high burden of multidrug-resistant tuberculosis (MDR-
TB), little is known about the management and treatment outcomes of MDR-TB patients in …

[HTML][HTML] Predictors of poor treatment outcomes in multidrug-resistant tuberculosis patients: a retrospective cohort study

A Javaid, I Ullah, H Masud, A Basit, W Ahmad… - Clinical Microbiology …, 2018 - Elsevier
Objectives We aimed to determine the characteristics, treatment outcomes and risk factors
for poor treatment outcomes among multidrug-resistant (MDR) tuberculosis (TB) patients in …