Circulating tumor DNA and liquid biopsy: opportunities, challenges, and recent advances in detection technologies
Cell-free DNA (cfDNA) refers to short fragments of acellular nucleic acids detectable in
almost all body fluids, including blood, and is involved in various physiological and …
almost all body fluids, including blood, and is involved in various physiological and …
A comprehensive overview on alkaline phosphatase targeting and reporting assays
Alkaline phosphatase (ALP) is an enzyme that catalyzes the dephosphorylation of various
vital nucleic acids and proteins. A broad range of physiological and pathological processes …
vital nucleic acids and proteins. A broad range of physiological and pathological processes …
Advanced liquid biopsy technologies for circulating biomarker detection
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …
and identifying tumor genomes in body fluid samples. Detection of tumor origin …
DNA clutch probes for circulating tumor DNA analysis
J Das, I Ivanov, EH Sargent… - Journal of the American …, 2016 - ACS Publications
Progress toward the development of minimally invasive liquid biopsies of disease is being
bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released …
bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released …
Assays for alkaline phosphatase that use L-ascorbic acid 2-phosphate as a substrate
Y Wu, W Chen, C Wang, D Xing - Coordination Chemistry Reviews, 2023 - Elsevier
Alkaline phosphatase (ALP) is a zinc-containing metalloprotein widely distributed in
mammalian tissues that catalyzes the dephosphorylation of a wide variety of phosphorylated …
mammalian tissues that catalyzes the dephosphorylation of a wide variety of phosphorylated …
[HTML][HTML] Current advances in detecting genetic and epigenetic biomarkers of colorectal cancer
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, extracellular …
second in terms of mortality. Recent studies have shown that various proteins, extracellular …
Recent advances in liquid biopsy technologies for cancer biomarker detection
N Soda, K Clack, MJA Shiddiky - Sensors & Diagnostics, 2022 - pubs.rsc.org
Gene mutation is associated with cancer and the dissemination of circulating biomarkers
through the blood represents a vital transitional step that exemplifies the shift from localized …
through the blood represents a vital transitional step that exemplifies the shift from localized …
Ultrasensitive electrochemical detection of miRNA-21 using a zinc finger protein specific to DNA–RNA hybrids
Both high sensitivity and high specificity are crucial for detection of miRNAs that have
emerged as important clinical biomarkers. Just Another Zinc finger proteins (JAZ, ZNF346) …
emerged as important clinical biomarkers. Just Another Zinc finger proteins (JAZ, ZNF346) …
Recent advancements in the utilization of indium tin oxide (ITO) in electroanalysis without surface modification
Indium tin oxide (ITO), as an electrode, has superiority over metal electrodes commonly
used for electroanalysis due to its low cost, low electrochemical background response, wide …
used for electroanalysis due to its low cost, low electrochemical background response, wide …
Graphene oxide-based simple and rapid detection of antibiotic resistance gene via quantum dot-labeled zinc finger proteins
With the increasing rise of antibiotic-resistant pathogens, a simple and rapid detection of
antibiotic resistance gene (ARG) is crucial to mitigate the spreading of antibiotic resistance …
antibiotic resistance gene (ARG) is crucial to mitigate the spreading of antibiotic resistance …