Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

[HTML][HTML] Lower-Risk Cannabis Use Guidelines (LRCUG) for reducing health harms from non-medical cannabis use: A comprehensive evidence and recommendations …

B Fischer, T Robinson, C Bullen, V Curran… - International Journal of …, 2022 - Elsevier
Background Cannabis use is common, especially among young people, and is associated
with risks for various health harms. Some jurisdictions have recently moved to …

[HTML][HTML] Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

J Moltke, C Hindocha - Journal of cannabis research, 2021 - Springer
Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: a double-blind randomized placebo-controlled …

YL Hurd, S Spriggs, J Alishayev… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Despite the staggering consequences of the opioid epidemic, limited nonopioid
medication options have been developed to treat this medical and public health crisis. This …

[HTML][HTML] Clinicians' guide to cannabidiol and hemp oils

HJ VanDolah, BA Bauer, KF Mauck - Mayo Clinic Proceedings, 2019 - Elsevier
Cannabidiol (CBD) oils are low tetrahydrocannabinol products derived from Cannabis sativa
that have become very popular over the past few years. Patients report relief for a variety of …

Cannabidiol for the treatment of cannabis use disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial

TP Freeman, C Hindocha, G Baio… - The Lancet …, 2020 - thelancet.com
Background A substantial and unmet clinical need exists for pharmacological treatment of
cannabis use disorders. Cannabidiol could offer a novel treatment, but it is unclear which …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

[HTML][HTML] The neuropsychopharmacology of cannabis: A review of human imaging studies

MAP Bloomfield, C Hindocha, SF Green… - Pharmacology & …, 2019 - Elsevier
The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

[HTML][HTML] Dosage, efficacy and safety of cannabidiol administration in adults: a systematic review of human trials

C Larsen, J Shahinas - Journal of clinical medicine research, 2020 - ncbi.nlm.nih.gov
Considering data from in vitro and in vivo studies, cannabidiol (CBD) seems to be a
promising candidate for the treatment of both somatic and psychiatric disorders. The aim of …

Therapeutic efficacy of cannabidiol (CBD): a review of the evidence from clinical trials and human laboratory studies

DJ Sholler, L Schoene, TR Spindle - Current addiction reports, 2020 - Springer
Rigorous, controlled evidence for the therapeutic efficacy of CBD is lacking for many health
conditions. Possible concerns with the use of CBD as a therapeutic include the potential for …