Valproic acid, a branching short chain fatty acid, is a popular drug to treat epilepsy and acts
as a mood-stabilizing drug. The obstruction of ion channels and Gamma Amino Butyrate …

Iodine-resistant cancers account for the vast majority of thyroid related mortality and, until
recently, there were limited therapeutic options. However, over the last decade our …

Background/Aim: There is a strong association between malignancy and histone
deacetylases (HDACs). Histone deacetylase inhibitors (HDACIs) are now being tested as …

Thyroid cancer is the most common malignancy of the endocrine system with a steadily
rising incidence. The term “thyroid cancer” encompasses a spectrum of subtypes, namely …

Colorectal cancer (CRC) comprises a heterogeneous group of gastrointestinal tract tumors.
It is a multifactorial disease, and a plethora of distinct factors are involved in its pathogenesis …

Anaplastic thyroid cancer (ATC) is one of the most lethal human malignancies, and it is
rapidly falling without any effective therapeutic options. Although radical surgery …

Background/Aim: Papillary Thyroid Cancer (PTC) is the most common type of endocrine
malignancy. Although PTC has an excellent prognosis, the recurrent or metastatic disease …

Type 2 diabetes mellitus (T2DM) is one of the most common metabolic disorders worldwide.
Recent research has indicated that sodium butyrate (NaB) affects glucose metabolism and …

Control of neovascularization with small molecules is a promising tactics. Here, we tested
the roles of sodium butyrate (NaBu) on the neovascularization and primary explained its …

Background Triple-negative breast cancer (TNBC) is the most aggressive type of cancer
without any approved targeted therapy. Epigenetic processes have a pivotal role in cancer …