The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host–pathogen interactions at the molecular level and is critical for devising …

Ticks transmit a greater variety of pathogenic agents that cause disease in humans and
animals than any other haematophagous arthropod, including Lyme disease, Rocky …

Extracellular vesicles are thought to facilitate pathogen transmission from arthropods to
humans and other animals. Here, we reveal that pathogen spreading from arthropods to the …

Pathogens must adapt to disparate environments in permissive host species, a feat that is
especially pronounced for vector-borne microbes, which transition between vertebrate hosts …

Tick-borne Anaplasma species are obligate, intracellular, bacterial pathogens that cause
important diseases globally in people, agricultural animals, and dogs. Targeted …

Ixodes scapula ris is a medically important tick that transmits several microbes to humans,
including rickettsial pathogen Anaplasma phagocytophilum. In nature, these ticks encounter …

Force loss in skeletal muscle exposed to eccentric contraction is often attributed to injury. We
show that EDL muscles from dystrophin-deficient mdx mice recover 65% of lost force within …

Human anaplasmosis caused by Anaplasma phagocytophilum is one of the most common
tick-borne diseases in the United States. The black-legged ticks, Ixodes scapularis, vector …

Catechol O-methyltransferase (COMT) is widely distributed in nature and installs a methyl
group onto one of the vicinal hydroxyl groups of a catechol derivative. Enzymes belonging to …

Tick-borne illnesses pose a serious concern to human and veterinary health and their
prevalence is on the rise. The interactions between ticks and the pathogens they carry are …