Targeting the gut and tumor microbiota in cancer
EM Park, M Chelvanambi, N Bhutiani, G Kroemer… - Nature medicine, 2022 - nature.com
Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
shaping cancer immunosurveillance and response to immunotherapy. Our understanding of …
shaping cancer immunosurveillance and response to immunotherapy. Our understanding of …
Colorectal cancer in inflammatory bowel disease: mechanisms and management
SC Shah, SH Itzkowitz - Gastroenterology, 2022 - Elsevier
Patients with inflammatory bowel disease (IBD) are at increased risk of developing
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …
Human gut microbiota in health and disease: Unveiling the relationship
The human gut possesses millions of microbes that define a complex microbial community.
The gut microbiota has been characterized as a vital organ forming its multidirectional …
The gut microbiota has been characterized as a vital organ forming its multidirectional …
The inflammatory pathogenesis of colorectal cancer
M Schmitt, FR Greten - Nature Reviews Immunology, 2021 - nature.com
The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …
made about the survival of patients or their response to therapy. Instead, studying the …
The intestinal microbiota and colorectal cancer
The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …
Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …
field of study. Gut microbiota modulation, with the aim to reverse established microbial …
Host–microbiota maladaptation in colorectal cancer
A Janney, F Powrie, EH Mann - Nature, 2020 - nature.com
Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is
characterized by the accumulation of mutations and a dysregulated immune response. Up to …
characterized by the accumulation of mutations and a dysregulated immune response. Up to …
Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
Dysbiosis of human gut microbiome in young-onset colorectal cancer
Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …