Radiolabelling of nanomaterials for medical imaging and therapy
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
Polymeric nanostructures for imaging and therapy
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …
although inefficient diagnosis and therapy are usually associated with either improper …
Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research
CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …
has decay characteristics that allow for positron emission tomography (PET) imaging and …
Shape effect of glyco-nanoparticles on macrophage cellular uptake and immune response
The shells of various poly (dl-lactide)-b-poly (acrylic acid)(PDLLA-b-PAA) spherical micelles
and poly (l-lactide)-b-poly (acrylic acid)(PLLA-b-PAA) cylindrical micelles were …
and poly (l-lactide)-b-poly (acrylic acid)(PLLA-b-PAA) cylindrical micelles were …
Nanoparticles labeled with positron emitting nuclides: advantages, methods, and applications
Y Liu, MJ Welch - Bioconjugate chemistry, 2012 - ACS Publications
Over the past decade, positron emitter labeled nanoparticles have been widely used in and
substantially improved for a range of diagnostic biomedical research. However, given …
substantially improved for a range of diagnostic biomedical research. However, given …
64Cu Core-Labeled Nanoparticles with High Specific Activity via Metal-Free Click Chemistry
D Zeng, NS Lee, Y Liu, D Zhou, CS Dence… - ACS …, 2012 - ACS Publications
A novel strategy based on metal-free “click” chemistry was developed for the copper-64
radiolabeling of the core in shell-cross-linked nanoparticles (SCK-NPs). Compared with Cu …
radiolabeling of the core in shell-cross-linked nanoparticles (SCK-NPs). Compared with Cu …
Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle
D Pan, TA Williams, A Senpan, JS Allen… - Journal of the …, 2009 - ACS Publications
A synthetic methodology for developing a polymeric nanoparticle for targeted computed
tomographic (CT) imaging is revealed in this manuscript. The work describes a new class of …
tomographic (CT) imaging is revealed in this manuscript. The work describes a new class of …
19F- and Fluorescently Labeled Micelles as Nanoscopic Assemblies for Chemotherapeutic Delivery
W Du, Z Xu, AM Nyström, K Zhang… - Bioconjugate …, 2008 - ACS Publications
Micelles from amphiphilic star-block copolymers, having a hydrophobic hyperbranched core
and amphiphilic fluoropolymer arms, were constructed as drug delivery agent assemblies. A …
and amphiphilic fluoropolymer arms, were constructed as drug delivery agent assemblies. A …
Facile, efficient approach to accomplish tunable chemistries and variable biodistributions for shell cross-linked nanoparticles
G Sun, A Hagooly, J Xu, AM Nyström, Z Li… - …, 2008 - ACS Publications
The in vivo behavior of shell cross-linked knedel-like (SCK) nanoparticles is shown to be
tunable via a straightforward and versatile process that advances SCKs as attractive …
tunable via a straightforward and versatile process that advances SCKs as attractive …
[HTML][HTML] Nanogels from metal-chelating crosslinkers as versatile platforms applied to copper-64 PET imaging of tumors and metastases
Metals are essential in medicine for both therapy and diagnosis. We recently created the first
metal-chelating nanogel imaging agent, which employed versatile, reproducible chemistry …
metal-chelating nanogel imaging agent, which employed versatile, reproducible chemistry …