Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Polymeric nanostructures for imaging and therapy

M Elsabahy, GS Heo, SM Lim, G Sun… - Chemical …, 2015 - ACS Publications
Medical diagnosis and therapy are essential for providing patients with proper care,
although inefficient diagnosis and therapy are usually associated with either improper …

Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research

CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …

Shape effect of glyco-nanoparticles on macrophage cellular uptake and immune response

Z Li, L Sun, Y Zhang, AP Dove, RK O'Reilly… - ACS macro …, 2016 - ACS Publications
The shells of various poly (dl-lactide)-b-poly (acrylic acid)(PDLLA-b-PAA) spherical micelles
and poly (l-lactide)-b-poly (acrylic acid)(PLLA-b-PAA) cylindrical micelles were …

Nanoparticles labeled with positron emitting nuclides: advantages, methods, and applications

Y Liu, MJ Welch - Bioconjugate chemistry, 2012 - ACS Publications
Over the past decade, positron emitter labeled nanoparticles have been widely used in and
substantially improved for a range of diagnostic biomedical research. However, given …

64Cu Core-Labeled Nanoparticles with High Specific Activity via Metal-Free Click Chemistry

D Zeng, NS Lee, Y Liu, D Zhou, CS Dence… - ACS …, 2012 - ACS Publications
A novel strategy based on metal-free “click” chemistry was developed for the copper-64
radiolabeling of the core in shell-cross-linked nanoparticles (SCK-NPs). Compared with Cu …

Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle

D Pan, TA Williams, A Senpan, JS Allen… - Journal of the …, 2009 - ACS Publications
A synthetic methodology for developing a polymeric nanoparticle for targeted computed
tomographic (CT) imaging is revealed in this manuscript. The work describes a new class of …

19F- and Fluorescently Labeled Micelles as Nanoscopic Assemblies for Chemotherapeutic Delivery

W Du, Z Xu, AM Nyström, K Zhang… - Bioconjugate …, 2008 - ACS Publications
Micelles from amphiphilic star-block copolymers, having a hydrophobic hyperbranched core
and amphiphilic fluoropolymer arms, were constructed as drug delivery agent assemblies. A …

Facile, efficient approach to accomplish tunable chemistries and variable biodistributions for shell cross-linked nanoparticles

G Sun, A Hagooly, J Xu, AM Nyström, Z Li… - …, 2008 - ACS Publications
The in vivo behavior of shell cross-linked knedel-like (SCK) nanoparticles is shown to be
tunable via a straightforward and versatile process that advances SCKs as attractive …

[HTML][HTML] Nanogels from metal-chelating crosslinkers as versatile platforms applied to copper-64 PET imaging of tumors and metastases

J Lux, AG White, M Chan, CJ Anderson, A Almutairi - Theranostics, 2015 - ncbi.nlm.nih.gov
Metals are essential in medicine for both therapy and diagnosis. We recently created the first
metal-chelating nanogel imaging agent, which employed versatile, reproducible chemistry …