[HTML][HTML] Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease

B Yu, S Wang - Theranostics, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) represent a large subgroup of RNAs that are longer than
200 nucleotides and have no apparent protein coding potential. They have diverse functions …

Noncoding RNAs in cardiovascular disease: current knowledge, tools and technologies for investigation, and future directions: a scientific statement from the american …

S Das, R Shah, S Dimmeler, JE Freedman… - Circulation: Genomic …, 2020 - Am Heart Assoc
Background: The discovery that much of the non–protein-coding genome is transcribed and
plays a diverse functional role in fundamental cellular processes has led to an explosion in …

Non-coding RNA in acute ischemic stroke: mechanisms, biomarkers and therapeutic targets

SW Wang, Z Liu, ZS Shi - Cell transplantation, 2018 - journals.sagepub.com
Non-coding RNAs (ncRNAs) are a class of functional RNAs that regulate gene expression in
a post-transcriptional manner. NcRNAs include microRNAs, long non-coding RNAs and …

CDR1as regulates α-synuclein-mediated ischemic brain damage by controlling miR-7 availability

SL Mehta, AK Chokkalla, S Bathula, V Arruri… - … Therapy-Nucleic Acids, 2023 - cell.com
Transient focal ischemia decreased microRNA-7 (miR-7) levels, leading to derepression of
its major target α-synuclein (α-Syn) that promotes secondary brain damage. Circular RNA …

lncRNAs: function and mechanism in cartilage development, degeneration, and regeneration

J Zhu, W Yu, Y Wang, K Xia, Y Huang, A Xu… - Stem cell research & …, 2019 - Springer
With the increasing incidence of cartilage-related diseases such as osteoarthritis (OA) and
intervertebral disc degeneration (IDD), heavier financial and social burdens need to be …

Long non-coding RNA TUG1 sponges Mir-145a-5p to regulate microglial polarization after oxygen-glucose deprivation

H Wang, S Liao, H Li, Y Chen, J Yu - Frontiers in molecular …, 2019 - frontiersin.org
Microglia plays a critical role in neuroinflammation after ischemic stroke by releasing diverse
inflammatory cytokines. Long non-coding RNA taurine up-regulated gene 1 (lncRNA TUG1) …

Dysregulated long non-coding RNAs in Parkinson's disease contribute to the apoptosis of human neuroblastoma cells

Y Fan, J Li, Q Yang, C Gong, H Gao, Z Mao… - Frontiers in …, 2019 - frontiersin.org
The molecular mechanism underlying Parkinson's disease (PD), an increasingly common
neurodegenerative disease, remains unclear. Long non-coding RNA (lncRNA) plays …

Should we care about early post-stroke rehabilitation? Not yet, but soon

SR Zeiler - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review Studies in humans and animal models show that most recovery
from impairment occurs in the first 1–3 months after stroke as a result of both spontaneous …

Pathophysiology of long non-coding RNAs in ischemic stroke

W Ren, X Yang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Stroke is a neurological disease with high disability and fatality rates, and ischemic stroke
accounts for 75% of all stroke cases. The underlying pathophysiologic processes of …

LncRNAs stand as potent biomarkers and therapeutic targets for stroke

J Fan, M Saft, N Sadanandan… - Frontiers in aging …, 2020 - frontiersin.org
Stroke is a major public health problem worldwide with a high burden of neurological
disability and mortality. Long noncoding RNAs (lncRNAs) have attracted much attention in …