Background A nutrient-rich maternal diet before and during pregnancy is associated with
improved fetal health, more appropriate birth weight, and increased rates of maternal and …

The recent growth of interest in developmental programming of physiological systems has
generally focused on the cardiovascular system (especially hypertension) and …

Nutritional constraints including not only caloric restriction or protein deficiency, but also
energy-dense diets affect metabolic health and frequently lead to obesity and insulin …

We examined the anogenital distance (AGD) plasticity in rats through the manipulation of the
androgen environment in utero and during puberty. Dams were treated from gestation days …

Arsenic induces reproductive disorders in pubertal males after prepubertal exposure.
However, it is unclear the extent to which those effects remain in testis and epididymis of …

Maternal protein restriction (MPR) in pregnancy causes life course organ dysfunction, but
few studies link the developmental origins of disease hypothesis to early aging. Suboptimal …

Type 2 diabetes mellitus (T2D) during pregnancy is characterized by high levels of reactive
oxygen species and pro‐inflammatory factors in the placenta. Once these reactive species …

Developmental programming predisposes offspring to metabolic, behavioural and
reproductive dysfunction in adult life. Evidence is accumulating that ageing phenotype and …

For the first time, juvenile toxicity of inorganic arsenic (As) was investigated in male rats,
focusing on reproductive effects. As is a metalloid naturally occurring in the environment …

Nutritional perturbation during gestation alters male reproductive development in rodents
and sheep. In cattle both the developmental trajectory of the feto–placental unit and its …