Neurons, perhaps more than any other cell type, depend on mitochondrial trafficking for their
survival. Recent studies have elucidated a motor/adaptor complex on the mitochondrial …

Mitochondria are multifunctional organelles that not only produce energy for the cell, but are
also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell …

Mitochondria are mobile organelles and cells regulate mitochondrial movement in order to
meet the changing energy needs of each cellular region. Ca 2+ signaling, which halts both …

“Germ granules” are cytoplasmic, nonmembrane-bound organelles unique to germline.
Germ granules share components with the P bodies and stress granules of somatic cells, but …

Recent studies show that pre-follicular mouse oogenesis takes place in germline cysts,
highly conserved groups of oogonial cells connected by intercellular bridges that develop as …

Mitochondria form a dynamic network responsible for energy production, calcium
homeostasis and cell signaling. Appropriate distribution of the mitochondrial network …

Interactions of mitochondria with the cytoskeleton are crucial for normal mitochondrial
function and for localization of the organelle at its sites of action within cells. Early studies …

Although mitochondrial DNA (mtDNA) is prone to mutation and few mtDNA repair
mechanisms exist, crippling mitochondrial mutations are exceedingly rare. Recent studies …

Mammalian germ cells divide mitotically and form nests of associated cells just prior to
entering meiosis. At least some nests contain germline cysts that arise by synchronous …

The Balbiani body is an evolutionarily conserved asymmetric aggregate of organelles that is
present in early oocytes of all animals examined, including humans. Although first identified …