Sex differences in depression: Insights from clinical and preclinical studies

RS Eid, AR Gobinath, LAM Galea - Progress in neurobiology, 2019 - Elsevier
Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Pathophysiological mechanisms implicated in postpartum depression

JL Payne, J Maguire - Frontiers in neuroendocrinology, 2019 - Elsevier
This review aims to summarize the diverse proposed pathophysiological mechanisms
contributing to postpartum depression, highlighting both clinical and basic science research …

Predictors of postpartum depression: a comprehensive review of the last decade of evidence

J Guintivano, T Manuck… - Clinical obstetrics and …, 2018 - journals.lww.com
Postpartum depression (PPD) is one of the most frequent complications of childbirth
affecting~ 500,000 women annually (prevalence 10% to 15%). Despite the documented …

Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

MA Schiele, K Domschke - Genes, Brain and Behavior, 2018 - Wiley Online Library
The pathogenesis of anxiety disorders is multifactorial, involving complex interactions
between biological factors, environmental influences and psychological mechanisms …

Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women

J Guintivano, PF Sullivan, AM Stuebe… - Psychological …, 2018 - cambridge.org
BackgroundRace, psychiatric history, and adverse life events have all been independently
associated with postpartum depression (PPD). However, the role these play together in …

Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation

BJ Ellis, AJ Horn, CS Carter, MH van IJzendoorn… - Clinical Psychology …, 2021 - Elsevier
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …

[HTML][HTML] Postpartum depression: Current status and possible identification using biomarkers

Y Yu, HF Liang, J Chen, ZB Li, YS Han… - Frontiers in …, 2021 - frontiersin.org
Postpartum depression (PPD) is a serious health issue that can affect about 15% of the
female population within after giving birth. It often conveys significant negative …

A review of DNA methylation in depression

D Chen, L Meng, F Pei, Y Zheng, J Leng - Journal of Clinical Neuroscience, 2017 - Elsevier
As one of the most common psychiatric disorders, depression has been a major public
health problem. Growing evidence suggests that epigenetic modification is essential in …

The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review

C Maud, J Ryan, JE McIntosh, CA Olsson - BMC psychiatry, 2018 - Springer
Abstract Background The neuropeptide Oxytocin (OXT) plays a central role in birthing,
mother-infant bonding and a broad range of related social behaviours in mammals. More …

[HTML][HTML] Epigenetics in depression and gut-brain axis: A molecular crosstalk

N Begum, A Mandhare, KP Tryphena… - Frontiers in Aging …, 2022 - frontiersin.org
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …