Objective: Synthesized a series of new thiourea (TU) derivatives, tested their antioxidant
activity, and investigated their expected biological activity by theoretical study …

Cancer can be definitely situated by means of the hysterical production of irregular cells in
every portion of the body. These atypical cells are mentioned as malignancy cells, tumor …

A series of new 1-(3-imino-2-oxoindolin-5-yl)-3-phenylurea derivatives were synthesized
starting from 5-aminoisatin; as a part of our program to compose multicomponent hybrid …

Heterocyclic compounds containing a bridge of nitrogen atom are of high importance in
medical chemistry and industrial applications Imidazo [1, 2-a] pyridines are a common and …

Breast cancer is the second leading cause of death in women. Fulvestrant and tamoxifen
(TAM) are the most extensively used medications to treat breast cancer. However, these …

Novel therapeutics are desperately needed for the difficult-to-treat and very lethal
malignancy known as hepatocellular carcinoma (HCC). The first drug now authorized for the …

Cancer is a disease triggered by an uncontrolled growth of a group of cells usually from a
single cell. Chemotherapy is a common and systematic therapy that involves the use of …

Molecular docking simulation and synthesis of five compounds of N2, N4-bis(2-(4-
substituted phenyl)-4-oxothiazolidin-3-yl)-3, 5-dimethyl-1H-pyrrole-2, 4-dicarboxamide was …

This dissertation explored the potential therapeutic applications of water and methanol
extracts of C. orbiculata and Tulbaghia violacea, indigenous to Southern Africa, targeting …

A novel series of pyrazole, oxadiazole and thiadiazole bearing Nabumetone moiety were
designed, synthesized, and evaluated for their anti-inflammatory activity against …