Is REDD1 a metabolic double agent? Lessons from physiology and pathology

FA Britto, K Dumas, S Giorgetti-Peraldi… - … of Physiology-Cell …, 2020 - journals.physiology.org
The Akt/mechanistic target of rapamycin (mTOR) signaling pathway governs macromolecule
synthesis, cell growth, and metabolism in response to nutrients and growth factors …

The regulation of adipocyte growth in white adipose tissue

Q Li, KL Spalding - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Adipocytes can increase in volume up to a thousand-fold, storing excess calories as
triacylglycerol in large lipid droplets. The dramatic morphological changes required of …

REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation

DK Lee, T Kim, J Byeon, M Park, S Kim, J Kim… - Nature …, 2022 - nature.com
Regulated in development and DNA damage response 1 (REDD1) expression is
upregulated in response to metabolic imbalance and obesity. However, its role in obesity …

The stress-responsive protein REDD1 and its pathophysiological functions

JY Kim, YG Kwon, YM Kim - Experimental & Molecular Medicine, 2023 - nature.com
Regulated in development and DNA damage-response 1 (REDD1) is a stress-induced
protein that controls various cellular functions, including metabolism, oxidative stress …

[HTML][HTML] The long winding road to the safer glucocorticoid receptor (GR) targeting therapies

EA Lesovaya, D Chudakova, G Baida, EM Zhidkova… - Oncotarget, 2022 - ncbi.nlm.nih.gov
Glucocorticoids (Gcs) are widely used to treat inflammatory diseases and hematological
malignancies, and despite the introduction of novel anti-inflammatory and anti-cancer …

Nutritional sensor REDD1 in cancer and inflammation: friend or foe?

EM Zhidkova, ES Lylova, DD Grigoreva… - International journal of …, 2022 - mdpi.com
Regulated in Development and DNA Damage Response 1 (REDD1)/DNA Damage-Induced
Transcript 4 (DDIT4) is an immediate early response gene activated by different stress …

Synephrine and Its Derivative Compound A: Common and Specific Biological Effects

SA Dodonova, EM Zhidkova, AA Kryukov… - International journal of …, 2023 - mdpi.com
This review is focused on synephrine, the principal phytochemical found in bitter orange and
other medicinal plants and widely used as a dietary supplement for weight loss/body fat …

Synephrine and Its Derivative CpdA: Common and Specific Biological Effects

SA Dodonova, E Zhidkova, AA Kryukov, T Valiev… - 2023 - preprints.org
This review is focused on synephrine, the principal phytochemical found in bitter orange and
other medicinal plants, and widely used as a dietary supplement for weight loss/body fat …

Contribuciones relativas de los receptores de glucocorticoides y mineralocorticoides en la biología cutánea

J Bigas - 2020 - digital.csic.es
[ES] Nuestra investigación se centra en comprender los mecanismos moleculares que
median las acciones de los glucocorticoides (GCs) en la fisiopatología de la piel mediante …