Tumor-induced inflammatory cytokines and the emerging diagnostic devices for cancer detection and prognosis
Chronic inflammation generated by the tumor microenvironment is known to drive cancer
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …
T cell fitness and autologous CAR T cell therapy in haematologic malignancy
PH Mehta, S Fiorenza, RM Koldej… - Frontiers in …, 2021 - frontiersin.org
A range of emerging therapeutic approaches for the treatment of cancer aim to induce or
augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy …
augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy …
Elevation of circulating TNF receptor 2 in cancer: A systematic meta-analysis for its potential as a diagnostic cancer biomarker
AER Kartikasari, E Cassar, MAM Razqan… - Frontiers in …, 2022 - frontiersin.org
High Tumor Necrosis Factor Receptor 2 (TNFR2) expression is characteristic of diverse
malignant cells during tumorigenesis. The protein is also expressed by many …
malignant cells during tumorigenesis. The protein is also expressed by many …
[HTML][HTML] Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
C Martín-Otal, A Lasarte-Cia, D Serrano… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background One of the main difficulties of adoptive cell therapies with chimeric antigen
receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The …
receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The …
Exposure of immunogenic tumor antigens in surrendered immunity and the significance of autologous tumor cell-based vaccination in precision medicine
CH Ke, YH Chiu, KC Huang, CS Lin - International journal of molecular …, 2022 - mdpi.com
The mechanisms by which immune systems identify and destroy tumors, known as
immunosurveillance, have been discussed for decades. However, several factors that lead …
immunosurveillance, have been discussed for decades. However, several factors that lead …
Elevated interleukin-6 levels in the circulation and peritoneal fluid of patients with ovarian cancer as a potential diagnostic biomarker: a systematic review and meta …
Ovarian cancer (OC) is one of the most lethal cancers, largely due to a late diagnosis. This
study aimed to provide a comprehensive meta-analysis on the diagnostic performance of IL6 …
study aimed to provide a comprehensive meta-analysis on the diagnostic performance of IL6 …
Ibrutinib protects T cells in patients with CLL from proliferation-induced senescence
Abstract Background The development of Bruton's tyrosine kinase inhibitors (BTKi) for the
treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and …
treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and …
Potential impact of human cytomegalovirus infection on immunity to ovarian tumours and cancer progression
Ovarian cancer (OC) is one of the most common, and life-threatening gynaecological cancer
affecting females. Almost 75% of all OC cases are diagnosed at late stages, where the 5 …
affecting females. Almost 75% of all OC cases are diagnosed at late stages, where the 5 …
[PDF][PDF] Effect of the treatment stage on the serum levels of selected cytokines and antioxidant enzymes in patients with tumors of the reproductive organs.
S Wieder-Huszla, A Chudecka-Głaz… - European Review for …, 2023 - ppm.pum.edu.pl
OBJECTIVE: Chronic inflammation along with concomitant oxidative stress contributes to an
increased risk of cancer development. The aim of this study was to analyze selected …
increased risk of cancer development. The aim of this study was to analyze selected …
Occult cancer in patients with unprovoked venous thromboembolism: A nested case-control study
V Sánchez-López, S Marín-Romero… - American Journal of …, 2024 - academic.oup.com
Objectives Detecting occult cancer in patients with unprovoked venous thromboembolism
(VTE) remains a significant challenge. Our objective was to investigate the potential …
(VTE) remains a significant challenge. Our objective was to investigate the potential …