Chronic inflammation generated by the tumor microenvironment is known to drive cancer
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …

A range of emerging therapeutic approaches for the treatment of cancer aim to induce or
augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy …

High Tumor Necrosis Factor Receptor 2 (TNFR2) expression is characteristic of diverse
malignant cells during tumorigenesis. The protein is also expressed by many …

Ovarian cancer (OC) is one of the most lethal cancers, largely due to a late diagnosis. This
study aimed to provide a comprehensive meta-analysis on the diagnostic performance of IL6 …

Abstract Background The development of Bruton's tyrosine kinase inhibitors (BTKi) for the
treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and …

Ovarian cancer (OC) is one of the most common, and life-threatening gynaecological cancer
affecting females. Almost 75% of all OC cases are diagnosed at late stages, where the 5 …

Background One of the main difficulties of adoptive cell therapies with chimeric antigen
receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The …

The mechanisms by which immune systems identify and destroy tumors, known as
immunosurveillance, have been discussed for decades. However, several factors that lead …

OBJECTIVE: Chronic inflammation along with concomitant oxidative stress contributes to an
increased risk of cancer development. The aim of this study was to analyze selected …

Multiple myeloma (MM) is the third most common malignant neoplasm of the hematological
system. It often develops from monoclonal gammopathy of undetermined significance …