Tumor-induced inflammatory cytokines and the emerging diagnostic devices for cancer detection and prognosis

AER Kartikasari, CS Huertas, A Mitchell… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammation generated by the tumor microenvironment is known to drive cancer
initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor …

T cell fitness and autologous CAR T cell therapy in haematologic malignancy

PH Mehta, S Fiorenza, RM Koldej… - Frontiers in …, 2021 - frontiersin.org
A range of emerging therapeutic approaches for the treatment of cancer aim to induce or
augment endogenous T cell responses. Chimeric antigen receptor (CAR) T cell therapy …

Elevation of circulating TNF receptor 2 in cancer: A systematic meta-analysis for its potential as a diagnostic cancer biomarker

AER Kartikasari, E Cassar, MAM Razqan… - Frontiers in …, 2022 - frontiersin.org
High Tumor Necrosis Factor Receptor 2 (TNFR2) expression is characteristic of diverse
malignant cells during tumorigenesis. The protein is also expressed by many …

[HTML][HTML] Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

C Martín-Otal, A Lasarte-Cia, D Serrano… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background One of the main difficulties of adoptive cell therapies with chimeric antigen
receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The …

Exposure of immunogenic tumor antigens in surrendered immunity and the significance of autologous tumor cell-based vaccination in precision medicine

CH Ke, YH Chiu, KC Huang, CS Lin - International journal of molecular …, 2022 - mdpi.com
The mechanisms by which immune systems identify and destroy tumors, known as
immunosurveillance, have been discussed for decades. However, several factors that lead …

Elevated interleukin-6 levels in the circulation and peritoneal fluid of patients with ovarian cancer as a potential diagnostic biomarker: a systematic review and meta …

H Amer, AER Kartikasari, M Plebanski - Journal of Personalized Medicine, 2021 - mdpi.com
Ovarian cancer (OC) is one of the most lethal cancers, largely due to a late diagnosis. This
study aimed to provide a comprehensive meta-analysis on the diagnostic performance of IL6 …

Ibrutinib protects T cells in patients with CLL from proliferation-induced senescence

JE Davis, C Sharpe, K Mason, CS Tam… - Journal of Translational …, 2021 - Springer
Abstract Background The development of Bruton's tyrosine kinase inhibitors (BTKi) for the
treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and …

Potential impact of human cytomegalovirus infection on immunity to ovarian tumours and cancer progression

M Cox, AER Kartikasari, PR Gorry, KL Flanagan… - Biomedicines, 2021 - mdpi.com
Ovarian cancer (OC) is one of the most common, and life-threatening gynaecological cancer
affecting females. Almost 75% of all OC cases are diagnosed at late stages, where the 5 …

[PDF][PDF] Effect of the treatment stage on the serum levels of selected cytokines and antioxidant enzymes in patients with tumors of the reproductive organs.

S Wieder-Huszla, A Chudecka-Głaz… - European Review for …, 2023 - ppm.pum.edu.pl
OBJECTIVE: Chronic inflammation along with concomitant oxidative stress contributes to an
increased risk of cancer development. The aim of this study was to analyze selected …

Occult cancer in patients with unprovoked venous thromboembolism: A nested case-control study

V Sánchez-López, S Marín-Romero… - American Journal of …, 2024 - academic.oup.com
Objectives Detecting occult cancer in patients with unprovoked venous thromboembolism
(VTE) remains a significant challenge. Our objective was to investigate the potential …