How do animals regenerate specialised tissues or their entire body after a traumatic injury,
how has this ability evolved and what are the genetic and cellular components underpinning …

In multicellular organisms, the specification, maintenance, and transmission of the germ cell
lineage to subsequent generations are critical processes that ensure species survival. A …

In most animals, pluripotency is irreversibly lost post gastrulation. By this stage, all
embryonic cells have already committed either to one of the somatic lineages (ectoderm …

We present an organism-wide, transcriptomic cell atlas of the hydrozoan medusa Clytia
hemisphaerica and describe how its component cell types respond to perturbation. Using …

Although adult pluripotent stem cells (aPSCs) are found in many animal lineages,
mechanisms for their formation during embryogenesis are unknown. Here, we leveraged …

Stem cells are pivotal for development and tissue homeostasis of multicellular animals, and
the quest for a gene toolkit associated with the emergence of stem cells in a common …

Neurogenesis initiates during early development and it continues through later
developmental stages and in adult animals to enable expansion, remodeling, and …

The study of stem cells in cnidarians has a history spanning hundreds of years, but it has
primarily focused on the hydrozoan genus Hydra. While Hydra has a number of self …

The capacity to regenerate lost or injured body parts is a widespread feature within
metazoans and has intrigued scientists for centuries. One of the most extreme types of …

Like most bilaterian animals, the annelid Platynereis dumerilii generates the majority of its
body axis in an anterior to posterior temporal progression with new segments added …