International consensus based review and recommendations for minimum reporting standards in research on transcutaneous vagus nerve stimulation (version 2020)

AD Farmer, A Strzelczyk, A Finisguerra… - Frontiers in human …, 2021 - frontiersin.org
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus
nerve stimulation (tVNS) across basic, translational and clinical research …

Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders

S Breit, A Kupferberg, G Rogler, G Hasler - Frontiers in psychiatry, 2018 - frontiersin.org
The vagus nerve represents the main component of the parasympathetic nervous system,
which oversees a vast array of crucial bodily functions, including control of mood, immune …

Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice

E Siopi, M Galerne, M Rivagorda, S Saha… - Molecular …, 2023 - nature.com
Chronic stress constitutes a major risk factor for depression that can disrupt various aspects
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …

Critical review of transcutaneous vagus nerve stimulation: challenges for translation to clinical practice

JYY Yap, C Keatch, E Lambert, W Woods… - Frontiers in …, 2020 - frontiersin.org
Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can
elicit therapeutic effects that are similar to those produced by its invasive counterpart, vagus …

Transcutaneous vagus nerve stimulation in humans induces pupil dilation and attenuates alpha oscillations

O Sharon, F Fahoum, Y Nir - Journal of Neuroscience, 2021 - Soc Neuroscience
Vagus nerve stimulation (VNS) is widely used to treat drug-resistant epilepsy and
depression. While the precise mechanisms mediating its long-term therapeutic effects are …

Neurophysiologic effects of transcutaneous auricular vagus nerve stimulation (taVNS) via electrical stimulation of the tragus: a concurrent taVNS/fMRI study and …

BW Badran, LT Dowdle, OJ Mithoefer, NT LaBate… - Brain stimulation, 2018 - Elsevier
Background Electrical stimulation of the auricular branch of the vagus nerve (ABVN) via
transcutaneous auricular vagus nerve stimulation (taVNS) may influence afferent vagal …

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation

DR Hulsey, JR Riley, KW Loerwald… - Experimental …, 2017 - Elsevier
Vagus nerve stimulation (VNS) has emerged as a therapy to treat a wide range of
neurological disorders, including epilepsy, depression, stroke, and tinnitus. Activation of …

A review of parameter settings for invasive and non-invasive vagus nerve stimulation (VNS) applied in neurological and psychiatric disorders

SL Thompson, GH O'Leary, CW Austelle… - Frontiers in …, 2021 - frontiersin.org
Vagus nerve stimulation (VNS) is an established form of neuromodulation with a long history
of promising applications. Earliest reports of VNS in the literature date to the late 1800's in …

When the locus coeruleus speaks up in sleep: recent insights, emerging perspectives

A Osorio-Forero, N Cherrad, L Banterle… - International journal of …, 2022 - mdpi.com
For decades, numerous seminal studies have built our understanding of the locus coeruleus
(LC), the vertebrate brain's principal noradrenergic system. Containing a numerically small …