Older adult participation in cancer clinical trials: a systematic review of barriers and interventions

MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Human papillomavirus as a driver of head and neck cancers

ME Sabatini, S Chiocca - British journal of cancer, 2020 - nature.com
The human papillomavirus (HPV) family includes more than 170 different types of virus that
infect stratified epithelium. High-risk HPV is well established as the primary cause of cervical …

Deintensification of treatment for human papillomavirus-related oropharyngeal cancer: Current state and future directions

EO Bigelow, TY Seiwert, C Fakhry - Oral oncology, 2020 - Elsevier
Human papillomavirus (HPV)-related oropharyngeal squamous cell cancer (OPSCC) has
emerged as a distinct clinical entity of head and neck cancer with expected high survival …

Survey of oncologists' perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials

AB Kornblith, M Kemeny, BL Peterson, J Wheeler… - Cancer, 2002 - Wiley Online Library
BACKGROUND Prior research has documented the under‐representation in clinical trials of
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …

Oropharyngeal cancer is no longer a disease of younger patients and the prognostic advantage of Human Papillomavirus is attenuated among older patients: Analysis …

EM Rettig, M Zaidi, F Faraji, DW Eisele, M El Asmar… - Oral oncology, 2018 - Elsevier
Objectives HPV-positive oropharyngeal cancer (OPC) patients have been observed to be
younger than patients with HPV-negative OPC at diagnosis. We evaluated recent trends in …

Survival outcomes with concurrent chemoradiation for elderly patients with locally advanced head and neck cancer according to the National Cancer Data Base

A Amini, BL Jones, JD McDermott, HS Serracino… - Cancer, 2016 - Wiley Online Library
BACKGROUND The overall survival (OS) benefit of concurrent chemoradiotherapy (CRT) for
head and neck squamous cell carcinoma patients older than 70 years is debated. This study …

[HTML][HTML] Phototheranostic porphyrin nanoparticles enable visualization and targeted treatment of head and neck cancer in clinically relevant models

N Muhanna, CS Jin, E Huynh, H Chan, Y Qiu… - Theranostics, 2015 - ncbi.nlm.nih.gov
Head and neck cancer is the fifth most common type of cancer worldwide and remains
challenging for effective treatment due to the proximity to critical anatomical structures in the …

Predictive factors for chemoradiation-induced oral mucositis and dysphagia in head and neck cancer: a scoping review

AJ Nicol, JCF Ching, VCW Tam, KCK Liu, VWS Leung… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer is the seventh-most prevalent cancer worldwide.
Despite advances in treatment, many patients suffer from chemoradiation-induced oral …

Impact of early nutrition counseling in head and neck cancer patients with normal nutritional status

YW Ho, KY Yeh, SW Hsueh, CY Hung, CH Lu… - Supportive Care in …, 2021 - Springer
Background Nutritional counseling is frequently overlooked in cancer patients with normal
nutritional status. This study aimed to evaluate the impact of nutritional counseling in head …

Community oncologists' decision-making for treatment of older patients with cancer

SG Mohile, A Magnuson, C Pandya, C Velarde… - Journal of the National …, 2018 - jnccn.org
Background: This study's objectives were to describe community oncologists' beliefs about
and confidence with geriatric care and to determine whether geriatric-relevant information …