Neutrophil heterogeneity in cancer: from biology to therapies

P Lecot, M Sarabi, M Pereira Abrantes… - Frontiers in …, 2019 - frontiersin.org
Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …

Neutrophils in triple-negative breast cancer: an underestimated player with increasingly recognized importance

C Zheng, X Xu, M Wu, L Xue, J Zhu, H Xia, S Ding… - Breast Cancer …, 2023 - Springer
Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, with limited
therapeutic options readily available. Immunotherapy such as immune checkpoint inhibition …

Prognostic value of neutrophil‐to‐lymphocyte ratio and platelet‐to‐lymphocyte ratio for breast cancer patients: An updated meta‐analysis of 17079 individuals

W Guo, X Lu, Q Liu, T Zhang, P Li, W Qiao… - Cancer …, 2019 - Wiley Online Library
Aims This study aimed to evaluate the prognostic effect of neutrophil‐to‐lymphocyte ratio
(NLR) and platelet‐to‐lymphocyte ratio (PLR) for patients with breast cancer (BC). Methods …

Neutrophil to lymphocyte ratio as prognostic and predictive factor in breast cancer patients: a systematic review

I Corbeau, W Jacot, S Guiu - Cancers, 2020 - mdpi.com
Inflammatory blood markers (IBM), such as the neutrophil to lymphocyte ratio (NLR), have
emerged as potential prognostic factors in various cancers, including breast cancer (BC) …

Tumor-associated neutrophils as new players in immunosuppressive process of the tumor microenvironment in breast cancer

F Hajizadeh, LA Maleki, M Alexander, MV Mikhailova… - Life sciences, 2021 - Elsevier
Despite the conventional reputation of neutrophils to have antibacterial properties, recent
studies have put emphasis and are interested in the role of neutrophils in the spread and …

Prognostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in gastric cancer

Y Zhang, JJ Lu, YP Du, CX Feng, LQ Wang, MB Chen - Medicine, 2018 - journals.lww.com
The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been
presented to be a prognostic indicator in several types of cancer. However, these issues …

Neutrophil in the pancreatic tumor microenvironment

L Jin, HS Kim, J Shi - Biomolecules, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a poor prognosis and low
survival rates. PDAC is characterized by a fibroinflammatory tumor microenvironment …

Prognostic role of preoperative circulating systemic inflammatory response markers in primary breast cancer: meta-analysis

F Savioli, ES Morrow, RD Dolan, L Romics… - British Journal of …, 2022 - academic.oup.com
Background Circulating markers of the systemic inflammatory response are prognostic in
several cancers, but their role in operable breast cancer is unclear. A systematic review and …

Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression

Z Mahmud, A Rahman, ID Mishu, Y Kabir - Cancer and Metastasis …, 2022 - Springer
Cancer is considered a major public health concern worldwide and is characterized by an
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …

[HTML][HTML] Prognostic role and clinical association of tumor-infiltrating lymphocyte, programmed death ligand-1 expression with neutrophil-lymphocyte ratio in locally …

J Lee, DM Kim, A Lee - Cancer research and treatment …, 2019 - synapse.koreamed.org
Purpose Tumor-infiltrating lymphocyte (TIL), programmed death-ligand 1 (PD-L1)
expression and neutrophil-to-lymphocyte ratio (NLR) is associated to immunogenicity and …