Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
[HTML][HTML] The role of Mfsd2a in nervous system diseases
B Huang, X Li - Frontiers in Neuroscience, 2021 - frontiersin.org
Major facilitator superfamily (MFS) is the maximum and most diversified membrane
transporter, acting as uniporters, symporters and antiporters. MFS is considered to have a …
transporter, acting as uniporters, symporters and antiporters. MFS is considered to have a …
[HTML][HTML] Choline: exploring the growing science on its benefits for moms and babies
The importance of ensuring adequate choline intakes during pregnancy is increasingly
recognized. Choline is critical for a number of physiological processes during the prenatal …
recognized. Choline is critical for a number of physiological processes during the prenatal …
Metabolite dynamics and phytochemistry of a soy whey-based beverage bio-transformed by water kefir consortium
F Azi, C Tu, L Meng, L Zhiyu, MT Cherinet… - Food Chemistry, 2021 - Elsevier
Integrated metabolomic and metagenomic techniques were used to study the metabolite
dynamics and phytochemistry of a soy whey-based beverage bio-transformed by water kefir …
dynamics and phytochemistry of a soy whey-based beverage bio-transformed by water kefir …
Sex-specific responses in placental fatty acid oxidation, esterification and transfer capacity to maternal obesity
TL Powell, K Barner, L Madi, M Armstrong… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Fatty acid metabolism and oxidation capacity in the placenta, which likely affects the rate
and composition of lipid delivered to the fetus remains poorly understood. Long chain …
and composition of lipid delivered to the fetus remains poorly understood. Long chain …
[HTML][HTML] Lipid metabolism is dysregulated before, during and after pregnancy in a mouse model of gestational diabetes
S Furse, DS Fernandez-Twinn, D Chiarugi… - International Journal of …, 2021 - mdpi.com
The aim of the current study was to test the hypothesis that maternal lipid metabolism was
modulated during normal pregnancy and that these modulations are altered in gestational …
modulated during normal pregnancy and that these modulations are altered in gestational …
[HTML][HTML] Prenatal choline supplement in a maternal obesity model modulates offspring hepatic lipidomes
Maternal obesity during pregnancy adversely impacts offspring health, predisposing them to
chronic metabolic diseases characterized by insulin resistance, dysregulated macronutrient …
chronic metabolic diseases characterized by insulin resistance, dysregulated macronutrient …
Comparative lipidomics of chick yolk sac during the embryogenesis provides insight into understanding the development-related lipid supply
Yolk sac (YS, include the yolk content) at different chick embryogenesis stages possesses
varying lipid distributions, which are nutrition-influencing factors for the health of an early …
varying lipid distributions, which are nutrition-influencing factors for the health of an early …
[HTML][HTML] Ontogeny of circulating lipid metabolism in pregnancy and early childhood–a longitudinal population study
S Burugupalli, AAT Smith, G Oshlensky, K Huynh… - Elife, 2022 - elifesciences.org
Background: There is mounting evidence that in utero and early life exposures may
predispose an individual to metabolic disorders in later life; and dysregulation of lipid …
predispose an individual to metabolic disorders in later life; and dysregulation of lipid …
Placental fatty acid transport across late gestation in a baboon model of intrauterine growth restriction
SS Chassen, V Ferchaud‐Roucher… - The Journal of …, 2020 - Wiley Online Library
Key points Intrauterine growth restriction (IUGR) is associated with perinatal morbidity and
increased risk of lifelong disease, including neurodevelopmental impairment. Fatty acids …
increased risk of lifelong disease, including neurodevelopmental impairment. Fatty acids …