BACKGROUND Hyperglycemia can result from a loss of pancreatic beta-cells or a decline in
their function leading to decreased insulin secretion or may arise from insulin resistance and …

Diabetes mellitus (DM) represents one of the greatest threats to human health all over the
world. The incidence of DM is rising rapidly also including children and young persons of …

Diabetes mellitus (DM) is a prevalent chronic disease. Type 1 DM (T1DM) is a metabolic
disorder that is characterized by hyperglycemia in the context of absolute lack of insulin …

Many studies have reported high prevalence of hypogonadism amongst the diabetic
patients suggesting the therapeutic benefits of testosterone hormone administration to these …

The antitumor properties of melatonin (MLT) are known for prostate cancer cells. This study
investigated whether MLT affects prostate maturation and interferes with tissue injuries …

Negative consequences of diabetes on the prostate such as involution are associated with
diminished testosterone, insulin deficiency, and hyperglycemia. The contributions of …

Background Both benign prostatic hyperplasia (BPH) and Type-1 diabetes mellitus (T1DM)
share similar epidemiologic features and are all associated with the insulin-like growth factor …

Type 2 diabetes mellitus (T2DM) can cause prostate damage and affect male reproductive
function, but the underlying mechanisms are not completely understood. In this study, we …

Clinical and experimental studies have shown that exposure to adverse conditions during
the critical stages of embryonic, fetal or neonatal development lead to a significantly …

Puberty is an important period for the growth and maturation of the male reproductive
system, and is also a critical window for endocrine or environmental interference. The …