[HTML][HTML] PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases
HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy
A Narmani, R Jahedi… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction During the last decades, the ever-increasing proportion of patients with cancer
has been led to serious concerns worldwide. Therefore, the development and use of novel …
has been led to serious concerns worldwide. Therefore, the development and use of novel …
[HTML][HTML] Rapidly dissolving microneedles for the delivery of steroid-loaded nanoparticles intended for the treatment of inflammatory skin diseases
H Dawud, A Abu Ammar - Pharmaceutics, 2023 - mdpi.com
Drug delivery through the skin has immense advantages compared to other routes of
administration and offers an optimal way to treat inflammatory skin diseases, where …
administration and offers an optimal way to treat inflammatory skin diseases, where …
Controlled therapeutic delivery of CO from carbon monoxide-releasing molecules (CORMs)
Carbon monoxide (CO) has been regarded as a “silent killer” for its toxicity toward biological
systems. However, a low concentration of endogenously produced CO has shown a number …
systems. However, a low concentration of endogenously produced CO has shown a number …
Recent advances in PLGA-based nanofibers as anticancer drug delivery systems
MS Razavi, A Abdollahi, A Malek-Khatabi… - Journal of Drug Delivery …, 2023 - Elsevier
Polymeric nanofibers (NFs) as biocompatible and biodegradable scaffolds have been
investigated in numerous biomedical fields such as cancer treatment and drug delivery …
investigated in numerous biomedical fields such as cancer treatment and drug delivery …
Transferrin-conjugated PLGA nanoparticles for Co-delivery of temozolomide and bortezomib to glioblastoma cells
MJ Ramalho, ID Torres, JA Loureiro… - ACS Applied Nano …, 2023 - ACS Publications
Glioblastoma (GBM) represents almost half of primary brain tumors, and its standard
treatment with the alkylating agent temozolomide (TMZ) is not curative. Treatment failure is …
treatment with the alkylating agent temozolomide (TMZ) is not curative. Treatment failure is …
[HTML][HTML] Innovative delivery and release systems for antioxidants and other active substances in the treatment of cancer
Z Sezgin-Bayindir, S Losada-Barreiro… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the major diseases leading to death worldwide, and the fight against the
disease is still challenging. Cancer diseases are usually associated with increased oxidative …
disease is still challenging. Cancer diseases are usually associated with increased oxidative …
[HTML][HTML] Management of brain cancer and neurodegenerative disorders with polymer-based nanoparticles as a biocompatible platform
The blood–brain barrier (BBB) serves as a protective barrier for the central nervous system
(CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the …
(CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the …
[HTML][HTML] Recent advances in polymeric drug delivery systems for peripheral nerve regeneration
M Bianchini, S Micera, E Redolfi Riva - Pharmaceutics, 2023 - mdpi.com
When a traumatic event causes complete denervation, muscle functional recovery is highly
compromised. A possible solution to this issue is the implantation of a biodegradable …
compromised. A possible solution to this issue is the implantation of a biodegradable …
Sialic acid-decorated liposomes enhance the anti-cancer efficacy of docetaxel in tumor-associated macrophages
NP Tran, P Tran, SY Yoo, W Tangchang, S Lee… - Biomaterials …, 2023 - Elsevier
Tumor-associated macrophages (TAMs) in the tumor microenvironment potentially enhance
tumor growth and invasion through various mechanisms and are thus an essential factor in …
tumor growth and invasion through various mechanisms and are thus an essential factor in …