[HTML][HTML] The Characteristic of Virulence, Biofilm and Antibiotic Resistance of Klebsiella pneumoniae

G Wang, G Zhao, X Chao, L Xie, H Wang - International journal of …, 2020 - mdpi.com
Klebsiella pneumoniae is an important gram-negative opportunistic pathogen that causes a
variety of infectious diseases, including urinary tract infections, bacteremia, pneumonia, and …

[HTML][HTML] Role of the IL-23/IL-17 pathway in rheumatic diseases: an overview

C Schinocca, C Rizzo, S Fasano, G Grasso… - Frontiers in …, 2021 - frontiersin.org
Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19)
and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced …

Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Interleukin-6: designing specific therapeutics for a complex cytokine

C Garbers, S Heink, T Korn, S Rose-John - Nature reviews Drug …, 2018 - nature.com
Abstract Interleukin-6 (IL-6) is a pivotal cytokine with a diverse repertoire of physiological
functions that include regulation of immune cell proliferation and differentiation …

Klebsiella pneumoniae: going on the offense with a strong defense

MK Paczosa, J Mecsas - Microbiology and molecular biology …, 2016 - Am Soc Microbiol
Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …

[HTML][HTML] The immunobiology of the interleukin-12 family: room for discovery

EDT Wojno, CA Hunter, JS Stumhofer - Immunity, 2019 - cell.com
The discovery of interleukin (IL)-6 and its receptor subunits provided a foundation to
understand the biology of a group of related cytokines: IL-12, IL-23, and IL-27. These family …

The role of IL‐17 and related cytokines in inflammatory autoimmune diseases

T Kuwabara, F Ishikawa, M Kondo… - Mediators of …, 2017 - Wiley Online Library
Interleukin‐17 (IL‐17) induces the production of granulocyte colony‐stimulating factor (G‐
CSF) and chemokines such as CXCL1 and CXCL2 and is a cytokine that acts as an …

Mining the microbiota for microbial and metabolite-based immunotherapies

AN Skelly, Y Sato, S Kearney, K Honda - Nature Reviews Immunology, 2019 - nature.com
Trillions of microorganisms transit through and reside in the mammalian gastrointestinal tract
each day, collectively producing thousands of small molecules and metabolites with local …

Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

J Bustamante, S Boisson-Dupuis, L Abel… - Seminars in …, 2014 - Elsevier
Mendelian susceptibility to mycobacterial disease (MSMD) is a rare condition characterized
by predisposition to clinical disease caused by weakly virulent mycobacteria, such as BCG …

Early local immune defences in the respiratory tract

A Iwasaki, EF Foxman, RD Molony - Nature Reviews Immunology, 2017 - nature.com
The respiratory immune response consists of multiple tiers of cellular responses that are
engaged in a sequential manner in order to control infections. The stepwise engagement of …