Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
N Li, X Zhang, J Zhou, W Li, X Shu, Y Wu… - Advanced Drug Delivery …, 2022 - Elsevier
A growing body of multiscale biomechanical studies has been proposed to highlight the
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
mechanical cues in the development of hepatic fibrosis and cancer. At the cellular level …
The provocative roles of platelets in liver disease and cancer
P Kanikarla Marie, NW Fowlkes… - Frontiers in …, 2021 - frontiersin.org
Both platelets and the liver play important roles in the processes of coagulation and innate
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
immunity. Platelet responses at the site of an injury are rapid; their immediate activation and …
The liver, a functionalized vascular structure
The liver is not only the largest organ in the body but also the one playing one of the most
important role in the human metabolism as it is in charge of transforming toxic substances in …
important role in the human metabolism as it is in charge of transforming toxic substances in …
Analyzing the human liver vascular architecture by combining vascular corrosion casting and micro‐CT scanning: a feasibility study
Although a full understanding of the hepatic circulation is one of the keys to successfully
perform liver surgery and to elucidate liver pathology, relatively little is known about the …
perform liver surgery and to elucidate liver pathology, relatively little is known about the …
[图书][B] Electromagnetic fields in biology and medicine
MS Markov - 2015 - books.google.com
Electromagnetic field (EMF) modalities offer an alternative to the increasing use of
pharmaceutical products for therapeutic use. This book presents state-of-the-art EMF use in …
pharmaceutical products for therapeutic use. This book presents state-of-the-art EMF use in …
Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression
F Segovia-Miranda, H Morales-Navarrete, M Kücken… - Nature medicine, 2019 - nature.com
Early disease diagnosis is key to the effective treatment of diseases. Histopathological
analysis of human biopsies is the gold standard to diagnose tissue alterations. However, this …
analysis of human biopsies is the gold standard to diagnose tissue alterations. However, this …
Mathematical model of blood and interstitial flow and lymph production in the liver
JH Siggers, K Leungchavaphongse, CH Ho… - … and modeling in …, 2014 - Springer
We present a mathematical model of blood and interstitial flow in the liver. The liver is
treated as a lattice of hexagonal 'classic'lobules, which are assumed to be long enough that …
treated as a lattice of hexagonal 'classic'lobules, which are assumed to be long enough that …
[HTML][HTML] How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis
From the more than 100 liver diseases described, many of those with high incidence rates
manifest themselves by histopathological changes, such as hepatitis, alcoholic liver disease …
manifest themselves by histopathological changes, such as hepatitis, alcoholic liver disease …
A 3D porous media liver lobule model: the importance of vascular septa and anisotropic permeability for homogeneous perfusion
The hepatic blood circulation is complex, particularly at the microcirculatory level.
Previously, 2D liver lobule models using porous media and a 3D model using real …
Previously, 2D liver lobule models using porous media and a 3D model using real …
Hierarchical modeling of the liver vascular system
The liver plays a key role in the metabolic homeostasis of the whole organism. To carry out
its functions, it is endowed with a peculiar circulatory system, made of three main dendritic …
its functions, it is endowed with a peculiar circulatory system, made of three main dendritic …