Hereditary spastic paraplegia (HSP) is a syndrome designation describing inherited
disorders in which lower extremity weakness and spasticity are the predominant symptoms …

Hereditary spastic paraplegia (HSP) is a group of clinically and genetically heterogeneous
neurological disorders characterized by pathophysiologic hallmark of length-dependent …

Hereditary spastic paraplegia comprises a wide and heterogeneous group of inherited
neurodegenerative and neurodevelopmental disorders resulting from primary retrograde …

Hereditary spastic paraplegias (HSP) are a heterogeneous group of motor
neurodegenerative disorders that have the core clinical presentation of pyramidal syndrome …

Hereditary spastic paraplegia (SPG) is a clinically and genetically heterogeneous group of
neurodegenerative disorders that are clinically characterised by progressive spasticity and …

Mitochondrial diseases frequently manifest neuro-ophthalmologic symptoms and signs.
Because of the predilection of mitochondrial disorders to involve the optic nerves …

Although physical activity and sedentary behavior are moderately heritable, little is known
about the mechanisms that influence these traits. Combining data for up to 703,901 …

The hereditary spastic paraplegias (HSPs) comprise a large group of inherited neurologic
disorders. HSP is classified according to the mode of inheritance, the HSP locus when …

Hereditary spastic paraplegia (HSP) refers to inherited disorders in which spastic gait is
either the only feature or is a major syndrome feature. There are more than 70 genetic types …

Hereditary spastic paraplegias are a clinically and genetically heterogeneous group of gait
disorders. Their pathological hallmark is a length-dependent distal axonopathy of nerve …