Despite advances in cytotoxic treatments, colorectal cancer remains a leading cause of
death. Metastatic colorectal cancer (mCRC) patients have a poor prognosis despite …

Signaling proteins in eukaryotes usually comprise a catalytic domain coupled to one or
several interaction domains, such as SH2 and SH3 domains. An additional class of proteins …

Current study in the heterogeneity and physiological behavior of tumor cells is limited by the
fluorescence in situ hybridization technology in terms of probe assembly efficiency …

Human epidermal growth factor receptor 3 (HER3) is a member of the transmembrane
receptor tyrosine kinase family. Upregulation of HER3 pathway has been implicated as a …

Oncolytic viruses (OVs) are attenuated viruses that have been engineered to selectively
infect and kill cancer cells. OVs exert anti-tumour effects through different mechanisms that …

[ES] La familia de receptores tirosina quinasa ErbB/HER y sus ligandos juegan un papel
fundamental en las vías de señalización implicadas en la proliferación, migración y …