Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …

Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Stress influences circulating inflammatory markers, and these effects may mediate the
influence of psychosocial factors on cardiovascular risk and other conditions such as …

Health disparities (differences in health by socioeconomic groups) are a pressing issue in
our society. This article provides an overview of a multilevel approach that seeks to …

Methods This paper arose from an extensive literature review undertaken in developing the
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …

Childhood adversity has been repeatedly and robustly linked to physical and mental illness
across the lifespan. Yet, the biological pathways through which this occurs remain unclear …

This study provides a comprehensive review of the published research on the association
between early life adversity and markers of inflammation in children and adolescents. We …

In this mini-review, we outline a model depicting the immunologic mechanisms by which
psychological stress can exacerbate clinical symptoms in patients with asthma. This model …

Previous research has clearly established associations between low socioeconomic status
(SES) and poor youth physical health outcomes. This article provides an overview of the …

▪ Abstract The prevalence of asthma in the United States is higher than in many other
countries in the world. Asthma, the most common chronic disease of childhood in the United …