o-Silylaryl Triflates: A Journey of Kobayashi Aryne Precursors
J Shi, L Li, Y Li - Chemical Reviews, 2021 - ACS Publications
Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …
Transition-metal-free coupling reactions
CL Sun, ZJ Shi - Chemical reviews, 2014 - ACS Publications
Transition-metal-catalyzed reactions have been studied since the very beginning of the past
century and represent a great success in organic chemistry, along with the birth and growth …
century and represent a great success in organic chemistry, along with the birth and growth …
Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies
Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …
investigation to assess their potential therapeutic significance. It possesses immeasurable …
Beyond a solvent: triple roles of dimethylformamide in organic chemistry
MM Heravi, M Ghavidel, L Mohammadkhani - RSC advances, 2018 - pubs.rsc.org
N, N-Dimethylformamide (DMF) is frequently used as an aprotic solvent in chemical
transformations in laboratories of academia as well as in those of chemical industry. In the …
transformations in laboratories of academia as well as in those of chemical industry. In the …
Recent advances in transition-metal-free carbon–carbon and carbon–heteroatom bond-forming reactions using arynes
This tutorial review is aimed at highlighting recent developments in transition-metal-free
carbon–carbon and carbon–heteroatom bond-forming reactions utilizing a versatile class of …
carbon–carbon and carbon–heteroatom bond-forming reactions utilizing a versatile class of …
Use of benzynes for the synthesis of heterocycles
AV Dubrovskiy, NA Markina, RC Larock - Organic & Biomolecular …, 2013 - pubs.rsc.org
About two decades after Kobayashi's discovery in 1983 of a very mild way of generating
highly reactive aryne intermediates, the synthetic community embraced o-(trimethylsilyl) aryl …
highly reactive aryne intermediates, the synthetic community embraced o-(trimethylsilyl) aryl …
N,N‐Dimethylformamide: A Multipurpose Building Block
S Ding, N Jiao - Angewandte Chemie International Edition, 2012 - Wiley Online Library
Often used as a common solvent for chemical reations and utilized widely in industry as a
reagent, N, N‐dimethylformamide (DMF) has played an important role in organic synthesis …
reagent, N, N‐dimethylformamide (DMF) has played an important role in organic synthesis …
ortho-Quinone methide (o-QM): a highly reactive, ephemeral and versatile intermediate in organic synthesis
MS Singh, A Nagaraju, N Anand, S Chowdhury - RSC advances, 2014 - pubs.rsc.org
Since its first observation in 1907, ortho-quinone methide (o-QM) has occupied a strategic
place within the framework of reactive intermediates in organic synthesis. In recent years, o …
place within the framework of reactive intermediates in organic synthesis. In recent years, o …
Ketenes and other cumulenes as reactive intermediates
AD Allen, TT Tidwell - Chemical Reviews, 2013 - ACS Publications
Reactive intermediates as recognized chemical entities date back for over a century, and
among the earliest examples were simple free radicals, as identified in 1879, when it was …
among the earliest examples were simple free radicals, as identified in 1879, when it was …
Visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids to coumarin derivatives under metal-free conditions
W Yang, S Yang, P Li, L Wang - Chemical Communications, 2015 - pubs.rsc.org
A visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids has been
developed. The arylsulfonylation of alkynes was performed at room temperature under metal …
developed. The arylsulfonylation of alkynes was performed at room temperature under metal …