Ischemic stroke caused by intracranial vascular occlusion has become increasingly
prevalent with considerable mortality and disability, which gravely burdens the global …

Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Brain glucose metabolism, including glycolysis, the pentose phosphate pathway, and
glycogen turnover, produces ATP for energetic support and provides the precursors for the …

Background The intestine of children with severe malnutrition (SM) shows structural and
functional changes that are linked to increased infection and mortality. SM dysregulates the …

Brain iron homeostasis is maintained through the normal function of blood–brain barrier and
iron regulation at the systemic and cellular levels, which is fundamental to normal brain …

Blood–brain barrier (BBB) dysfunction causing edema and hemorrhagic transformation is
one of the pathophysiological characteristics of stroke. Protection of BBB integrity has shown …

Autophagy is an essential intracellular process for cellular quality control. It enables cell
homeostasis through the selective degradation of harmful protein aggregates and damaged …

Ischemic stroke is a leading cause of mortality and disability. Diabetes mellitus,
characterized by hyperglycemia, is a common concomitant disease of ischemic stroke …

Blood–brain barrier (BBB) interface with multicellular structure controls strictly the entry of
varied circulating macromolecules from the blood-facing surface into the brain parenchyma …

Background: Increasing evidence suggests that acute traumatic spinal cord injury (SCI)-
induced defects in autophagy and autophagy-lysosomal pathway (ALP) may contribute to …